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Radiation-Associated Toxicities in Obese Women with Endometrial Cancer: More Than Just BMI?
المؤلفون المشاركون
Dandapani, Savita V.
Zhang, Ying
Jennelle, Richard
Lin, Yvonne G.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Purpose.
The study characterizes the impact of obesity on postoperative radiation-associated toxicities in women with endometrial cancer (EC).
Material and Methods.
A retrospective study identified 96 women with EC referred to a large urban institution’s radiation oncology practice for postoperative whole pelvic radiotherapy (WPRT) and/or intracavitary vaginal brachytherapy (ICBT).
Demographic and clinicopathologic data were obtained.
Toxicities were graded according to RTOG Acute Radiation Morbidity Scoring Criteria.
Follow-up period ranged from 1 month to 11 years (median 2 years).
Data were analyzed by χ2, logistic regression, and recursive partitioning analyses.
Results.
68 EC patients who received WPRT and/or ICBT were analyzed.
Median age was 52 years (29–73).
The majority were Hispanic (71%).
Median BMI at diagnosis was 34.5 kg/m2 (20.5–56.6 kg/m2).
BMI was independently associated with radiation-related cutaneous (p=0.022) and gynecologic-related (p=0.027) toxicities.
Younger women also reported more gynecologic-related toxicities (p=0.039).
Adjuvant radiation technique was associated with increased gastrointestinal- and genitourinary-related toxicities but not gynecologic-related toxicity.
Conclusions.
Increasing BMI was associated with increased frequency of gynecologic and cutaneous radiation-associated toxicities.
Additional studies to critically evaluate the radiation treatment dosing and treatment fields in obese EC patients are warranted to identify strategies to mitigate the radiation-associated toxicities in these women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dandapani, Savita V.& Zhang, Ying& Jennelle, Richard& Lin, Yvonne G.. 2015. Radiation-Associated Toxicities in Obese Women with Endometrial Cancer: More Than Just BMI?. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078817
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dandapani, Savita V.…[et al.]. Radiation-Associated Toxicities in Obese Women with Endometrial Cancer: More Than Just BMI?. The Scientific World Journal No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1078817
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dandapani, Savita V.& Zhang, Ying& Jennelle, Richard& Lin, Yvonne G.. Radiation-Associated Toxicities in Obese Women with Endometrial Cancer: More Than Just BMI?. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078817
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078817
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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