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Static Magnetic Field Attenuates Lipopolysaccharide-Induced Inflammation in Pulp Cells by Affecting Cell Membrane Stability
المؤلفون المشاركون
Lin, Che-Tong
Huang, Yung-Kai
Lee, Lin-Wen
Hsieh, Sung-Chih
Tsao, Jeng-Ting
Lew, Wei-Zhen
Chan, Ya-Hui
Huang, Haw-Ming
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
One of the causes of dental pulpitis is lipopolysaccharide- (LPS-) induced inflammatory response.
Following pulp tissue inflammation, odontoblasts, dental pulp cells (DPCs), and dental pulp stem cells (DPSCs) will activate and repair damaged tissue to maintain homeostasis.
However, when LPS infection is too serious, dental repair is impossible and disease may progress to irreversible pulpitis.
Therefore, the aim of this study was to examine whether static magnetic field (SMF) can attenuate inflammatory response of dental pulp cells challenged with LPS.
In methodology, dental pulp cells were isolated from extracted teeth.
The population of DPSCs in the cultured DPCs was identified by phenotypes and multilineage differentiation.
The effects of 0.4 T SMF on DPCs were observed through MTT assay and fluorescent anisotropy assay.
Our results showed that the SMF exposure had no effect on surface markers or multilineage differentiation capability.
However, SMF exposure increases cell viability by 15%.
In addition, SMF increased cell membrane rigidity which is directly related to higher fluorescent anisotropy.
In the LPS-challenged condition, DPCs treated with SMF demonstrated a higher tolerance to LPS-induced inflammatory response when compared to untreated controls.
According to these results, we suggest that 0.4 T SMF attenuates LPS-induced inflammatory response to DPCs by changing cell membrane stability.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hsieh, Sung-Chih& Tsao, Jeng-Ting& Lew, Wei-Zhen& Chan, Ya-Hui& Lee, Lin-Wen& Lin, Che-Tong…[et al.]. 2015. Static Magnetic Field Attenuates Lipopolysaccharide-Induced Inflammation in Pulp Cells by Affecting Cell Membrane Stability. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1078835
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hsieh, Sung-Chih…[et al.]. Static Magnetic Field Attenuates Lipopolysaccharide-Induced Inflammation in Pulp Cells by Affecting Cell Membrane Stability. The Scientific World Journal No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1078835
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hsieh, Sung-Chih& Tsao, Jeng-Ting& Lew, Wei-Zhen& Chan, Ya-Hui& Lee, Lin-Wen& Lin, Che-Tong…[et al.]. Static Magnetic Field Attenuates Lipopolysaccharide-Induced Inflammation in Pulp Cells by Affecting Cell Membrane Stability. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1078835
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078835
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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