Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1
المؤلفون المشاركون
Zhao, Fu-rong
Ding, Yao-zhong
Zhang, Qingxun
Fang, Yuzhen
Pan, Li
Lv, Jianliang
Zhang, Zhongwang
Zhou, Peng
Zhang, Jie
Wang, Yonglu
Zhang, Yongguang
Shao, Jun-jun
Lin, Tong
Chang, Hui-yun
Liu, Xin-sheng
Chen, Hao-tai
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-22
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Foot-and-mouth disease virus (FMDV) serotype Asia 1 was mostly endemic in Asia and then was responsible for economically important viral disease of cloven-hoofed animals, but the study on its selection and evolutionary process is comparatively rare.
In this study, we characterized 377 isolates from Asia collected up until 2012, including four vaccine strains.
Maximum likelihood analysis suggested that the strains circulating in Asia were classified into 8 different groups (groups I–VIII) or were unclassified (viruses collected before 2000).
On the basis of divergence time analyses, we infer that the TMRCA of Asia 1 virus existed approximately 86.29 years ago.
The result suggested that the virus had a high mutation rate (5.745 × 10−3 substitutions/site/year) in comparison to the other serotypes of FMDV VP1 gene.
Furthermore, the structural protein VP1 was under lower selection pressure and the positive selection occurred at many sites, and four codons (positions 141, 146, 151, and 169) were located in known critical antigenic residues.
The remaining sites were not located in known functional regions and were moderately conserved, and the reason for supporting all sites under positive selection remains to be elucidated because the power of these analyses was largely unknown.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Qingxun& Liu, Xin-sheng& Fang, Yuzhen& Pan, Li& Lv, Jianliang& Zhang, Zhongwang…[et al.]. 2015. Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1079069
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Qingxun…[et al.]. Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1. The Scientific World Journal No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1079069
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Qingxun& Liu, Xin-sheng& Fang, Yuzhen& Pan, Li& Lv, Jianliang& Zhang, Zhongwang…[et al.]. Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1079069
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1079069
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر