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Histological and morphological study of cerebrum and cerebellum of albino rats treated with antiandrogen flutamide
المؤلف
المصدر
Journal of Babylon University : Journal of Applied and Pure Sciences
العدد
المجلد 26، العدد 2 (28 فبراير/شباط 2018)، ص ص. 99-108، 10ص.
الناشر
تاريخ النشر
2018-02-28
دولة النشر
العراق
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The present study was aimed to assess the effects of antiandrogen flutamide on some histological and morphometric cerebrum and cerebellum tissue for white albino rats, Twenty five male rats were divided into five groups each group contains 5 animals, the first and second group regarded as positive and negative control, respectively, while the other groups was treated with flutamide drug orally for 28 days at concentrations of (8, 12, 25 mg/kg/day).
Histopathological results revealed that there is a significant increase in cell number of outer granular layers in cerebrum of the groups treated with 25 mg/kg/day compared to positive and negative control group as well as with other treated groups cerebrum, also the results of histopathological pointed that there were no significant differences in cerebellum tissue in all treated groups .
The morphometric results showed that there were no significant differences in thickness of cerebellar layers among different groups , therefore antiandrogen flutamide can be considered as a testosterone modulator.
To determine more precise effect of flutamide on the brain, further studies are needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hammud, Hanan Jasim. 2018. Histological and morphological study of cerebrum and cerebellum of albino rats treated with antiandrogen flutamide. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 26, no. 2, pp.99-108.
https://search.emarefa.net/detail/BIM-1094053
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hammud, Hanan Jasim. Histological and morphological study of cerebrum and cerebellum of albino rats treated with antiandrogen flutamide. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 26, no. 2 (2018), pp.99-108.
https://search.emarefa.net/detail/BIM-1094053
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hammud, Hanan Jasim. Histological and morphological study of cerebrum and cerebellum of albino rats treated with antiandrogen flutamide. Journal of Babylon University : Journal of Applied and Pure Sciences. 2018. Vol. 26, no. 2, pp.99-108.
https://search.emarefa.net/detail/BIM-1094053
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 106-108
رقم السجل
BIM-1094053
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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