Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations
المؤلفون المشاركون
Ieni, A.
Branca, Giovanni
Alberto Caruso, Rosario
Barresi, Valeria
Tuccari, Giovanni
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aim.
The role of mast cells in cell-cell immune interactions has received increasing attention, although their functional interaction with neutrophils still remains to be clarified in tumors.
The aim of the present study was to investigate the association between mast cells and neutrophils in a series of gastric carcinomas (GC).
Patients and Methods.
52 surgically resected GC specimens were routinely processed for both light and electron microscopy.
Only cases showing both mast cells and neutrophils in the tumor stroma were considered in the analysis.
Results.
Only 9 GC (M : F = 5 : 4; age range: 50–82 years) showed both mast cells and neutrophils in the tumor stroma.
At ultrathin sections, we identified heterotypic aggregation and intermingling of mast cells and neutrophils.
Mast cells had mature phenotype and showed full complement of granules with homogeneous, scroll, particle, and mixed pattern.
In addition, we found normal-appearing or early apoptosis showing neutrophils.
Conclusion.
Our histological findings showed the likely interaction between mast cells and neutrophils in GC.
We hypothesize that the granular content of mast cells may be released in small quantity through a mechanism called “kiss-and-run fusion,” which is alternative to well-known massive anaphylactic or piecemeal degranulation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ieni, A.& Barresi, Valeria& Branca, Giovanni& Alberto Caruso, Rosario& Tuccari, Giovanni. 2016. Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations. Analytical Cellular Pathology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1094970
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ieni, A.…[et al.]. Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations. Analytical Cellular Pathology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1094970
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ieni, A.& Barresi, Valeria& Branca, Giovanni& Alberto Caruso, Rosario& Tuccari, Giovanni. Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations. Analytical Cellular Pathology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1094970
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1094970
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر