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Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus
المؤلفون المشاركون
Chi, Shuhong
Yu, Yunxia
Zhang, Yurong
Yang, Jijuan
Yang, Lijuan
Xue, Jing
Li, Feng
Zhu, Caixia
Li, Haibo
Wang, Xuemei
Zhou, Shaolan
Ji, Chen
Liu, Xiaoming
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-16
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Serum concentrations of soluble interleukin-7 receptor (sIL-7R) and anti-C1q antibody have recently been identified as unique serological markers for lupus nephritis (LN) in patients with systemic lupus erythematosus (SLE).
In this study, we evaluated the correlation of serum sIL-7R and anti-C1q in SLE patients.
Methods.
Sera from 134 patients with SLE and 84 healthy cohorts were tested for levels of sIL-7R and anti-C1q antibodies in terms of ELISA.
Correlations of the sIL-7R and anti-C1q autoantibodies were evaluated.
Results.
The serum concentrations of sIL-7R and anti-C1q antibodies were significantly higher in SLE patients and LN patients in comparison with healthy individuals/controls and SLE patients with non-LN, respectively.
In addition, both sIL-7R and anti-C1q concentrations were found to significantly correlate with the SLE disease activity as evaluated by SLEDAI scores.
Interestingly, the serum sIL-7R concentration was strongly correlated with the level of anti-C1q antibodies (r=0.2871, p=0.0008) but not statistically correlated with other serological markers, including the anti-dsDNA and complements C3 and C4 concentrations in SLE patients.
Conclusion.
Both serum sIL-7R and anti-C1q antibodies were strongly associated with disease activity and LN in SLE patients, suggesting that they may be reliable serological markers for identification of SLE patients with active diseases and LN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chi, Shuhong& Xue, Jing& Li, Feng& Zhu, Caixia& Yu, Yunxia& Li, Haibo…[et al.]. 2016. Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus. Autoimmune Diseases،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1094988
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chi, Shuhong…[et al.]. Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus. Autoimmune Diseases No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1094988
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chi, Shuhong& Xue, Jing& Li, Feng& Zhu, Caixia& Yu, Yunxia& Li, Haibo…[et al.]. Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus. Autoimmune Diseases. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1094988
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1094988
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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