A Review on Potential Mechanisms of Terminalia chebula in Alzheimer’s Disease

المؤلفون المشاركون

Sadeghnia, Hamid Reza
Afshari, Amir R.
Mollazadeh, Hamid

المصدر

Advances in Pharmacological and Pharmaceutical Sciences

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-14، 14ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-01-28

دولة النشر

مصر

عدد الصفحات

14

التخصصات الرئيسية

علم الصيدلة

الملخص EN

The current management of Alzheimer’s disease (AD) focuses on acetylcholinesterase inhibitors (AChEIs) and NMDA receptor antagonists, although outcomes are not completely favorable.

Hence, novel agents found in herbal plants are gaining attention as possible therapeutic alternatives.

The Terminalia chebula (Family: Combretaceae) is a medicinal plant with a wide spectrum of medicinal properties and is reported to contain various biochemicals such as hydrolysable tannins, phenolic compounds, and flavonoids, so it may prove to be a good therapeutic alternative.

In this research, we reviewed published scientific literature found in various databases: PubMed, Science Direct, Scopus, Web of Science, Scirus, and Google Scholar, with the keywords: T.

chebula, AD, neuroprotection, medicinal plant, antioxidant, ellagitannin, gallotannin, gallic acid, chebulagic acid, and chebulinic acid.

This review shows that T.

chebula extracts and its constituents have AChEI and antioxidant and anti-inflammatory effects, all of which are currently relevant to the treatment of Alzheimer’s disease.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Afshari, Amir R.& Sadeghnia, Hamid Reza& Mollazadeh, Hamid. 2016. A Review on Potential Mechanisms of Terminalia chebula in Alzheimer’s Disease. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1096634

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Afshari, Amir R.…[et al.]. A Review on Potential Mechanisms of Terminalia chebula in Alzheimer’s Disease. Advances in Pharmacological and Pharmaceutical Sciences No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1096634

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Afshari, Amir R.& Sadeghnia, Hamid Reza& Mollazadeh, Hamid. A Review on Potential Mechanisms of Terminalia chebula in Alzheimer’s Disease. Advances in Pharmacological and Pharmaceutical Sciences. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1096634

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1096634