Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial
المؤلفون المشاركون
Sinha, Renu
Ray, Bikash Ranjan
Shende, Dilip
Kumar, Neeraj
Mohan, Virender Kumar
Maitra, Souvik
المصدر
Anesthesiology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-26
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
Efficacy of granisetron and combination of granisetron and dexamethasone was evaluated for prevention of postoperative nausea and vomiting (PONV) in children undergoing elective strabismus surgery.
Methods.
A total of 136 children (1–15 years) were included.
Children received either granisetron (40 mcg/kg) [group G] or combination of granisetron (40 mcg/kg) and dexamethasone (150 mcg/kg) [group GD].
Intraoperative fentanyl requirement and incidence and severity of oculocardiac reflex were assessed.
PONV severity was assessed for first 24 hours and if score was >2, it was treated with metoclopramide.
Postoperative analgesia was administered with intravenous fentanyl and ibuprofen.
Results.
The demographic profile, muscles operated, and fentanyl requirement were comparable.
Complete response to PONV in first 24 hours was observed in 75% (51/68) of children in group G and 76.9% (50/65) of children in group GD, which was comparable statistically ( p = 0.96 , Fisher exact test; OR 1.11, 95% CI 0.50, 2.46).
Incidence of PONV between 0 and 24 hours was comparable.
One child in group G required rescue antiemetic in first 24 hours and none of the children had severe PONV in group GD.
There was no significant difference in incidence or severity of oculocardiac reflex.
Conclusion.
Dexamethasone did not increase efficacy of granisetron for prevention of PONV in elective pediatric strabismus surgery.
Registration number of clinical trial was CTRI/2009/091/001000.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sinha, Renu& Shende, Dilip& Maitra, Souvik& Kumar, Neeraj& Ray, Bikash Ranjan& Mohan, Virender Kumar. 2016. Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial. Anesthesiology Research and Practice،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1096667
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sinha, Renu…[et al.]. Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial. Anesthesiology Research and Practice No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1096667
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sinha, Renu& Shende, Dilip& Maitra, Souvik& Kumar, Neeraj& Ray, Bikash Ranjan& Mohan, Virender Kumar. Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial. Anesthesiology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1096667
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1096667
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر