Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study
المؤلفون المشاركون
Shiferaw, Melashu Balew
Tulu, Ketema Tafess
Zegeye, Amtatachew Moges
Wubante, Amarech Asratie
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Liver disease has emerged as the most common non-AIDS-related cause of death in HIV patients.
However, there is limited data regarding this condition including our setting in Ethiopia.
Hence, liver enzyme abnormalities among highly active antiretroviral therapy (HAART) experienced and HAART naïve patients were assessed in this study.
A total of 164 HAART experienced and 164 HAART naïve patients were studied.
Blood specimen was collected to determine alanine aminotransferase (ALT) and aspartate aminotransferase (AST), CD4 count, and viral hepatitis.
The prevalence of liver enzyme abnormality was 20.1% and 22.0% among HAART experienced and HAART naïve patients, respectively.
The HAART experienced patients had higher mean ALT than HAART naïve patients ( P = 0.002 ).
Viral hepatitis (AOR = 6.02; 95% CI = 1.87–19.39), opportunistic infections (AOR = 2.91; 95% CI = 1.04–8.19), current CD4 count <200 cells/mm3 (AOR = 2.16; 95% CI = 1.06–4.39), and male sex (AOR = 1.83; 95% CI = 1.001–3.33) were associated with elevated ALT and/or AST.
In conclusion, liver enzyme abnormalities were high in both HAART experienced and HAART naïve HIV-1 infected patients.
Hence, monitoring and management of liver enzyme abnormalities in HIV-1 infected patients are important in our setting.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shiferaw, Melashu Balew& Tulu, Ketema Tafess& Zegeye, Amtatachew Moges& Wubante, Amarech Asratie. 2016. Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study. AIDS Research and Treatment،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096694
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shiferaw, Melashu Balew…[et al.]. Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study. AIDS Research and Treatment No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1096694
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shiferaw, Melashu Balew& Tulu, Ketema Tafess& Zegeye, Amtatachew Moges& Wubante, Amarech Asratie. Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study. AIDS Research and Treatment. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096694
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1096694
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر