Association of Aortic Compliance and Brachial Endothelial Function with Cerebral Small Vessel Disease in Type 2 Diabetes Mellitus Patients: Assessment with High-Resolution MRI
المؤلفون المشاركون
Zeng, Meng-Su
Shan, Yan
Lin, Jiang
Xu, Pengju
Lin, Huandong
Yan, Hongmei
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
To assess the possible association of aortic compliance and brachial endothelial function with cerebral small vessel disease in type 2 diabetes mellitus (DM2) patients by using 3.0 T high-resolution magnetic resonance imaging.
Methods.
Sixty-two clinically confirmed DM2 patients (25 women and 37 men; mean age: 56.8±7.5 years) were prospectively enrolled for noninvasive MR examinations of the aorta, brachial artery, and brain.
Aortic arch pulse wave velocity (PWV), flow-mediated dilation (FMD) of brachial artery, lacunar brain infarcts, and periventricular and deep white matter hyperintensities (WMHs) were assessed.
Pearson and Spearman correlation analysis were performed to analyze the association between PWV and FMD with clinical data and biochemical test results.
Univariable logistic regression analyses were used to analyze the association between PWV and FMD with cerebral small vessel disease.
Multiple logistic regression analyses were used to find out the independent predictive factors of cerebral small vessel disease.
Results.
Mean PWV was 6.73±2.00 m/s and FMD was 16.67±9.11%.
After adjustment for compounding factors, PWV was found significantly associated with lacunar brain infarcts (OR = 2.00; 95% CI: 1.14–3.2; P<0.05) and FMD was significantly associated with periventricular WMHs (OR = 0.82; 95% CI: 0.71–0.95; P<0.05).
Conclusions.
Quantitative evaluation of aortic compliance and endothelial function by using high-resolution MRI may be potentially useful to stratify DM2 patients with risk of cerebral small vessel disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shan, Yan& Lin, Jiang& Xu, Pengju& Zeng, Meng-Su& Lin, Huandong& Yan, Hongmei. 2016. Association of Aortic Compliance and Brachial Endothelial Function with Cerebral Small Vessel Disease in Type 2 Diabetes Mellitus Patients: Assessment with High-Resolution MRI. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096919
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shan, Yan…[et al.]. Association of Aortic Compliance and Brachial Endothelial Function with Cerebral Small Vessel Disease in Type 2 Diabetes Mellitus Patients: Assessment with High-Resolution MRI. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1096919
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shan, Yan& Lin, Jiang& Xu, Pengju& Zeng, Meng-Su& Lin, Huandong& Yan, Hongmei. Association of Aortic Compliance and Brachial Endothelial Function with Cerebral Small Vessel Disease in Type 2 Diabetes Mellitus Patients: Assessment with High-Resolution MRI. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096919
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1096919
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر