Assessment of Diagnostic and Prognostic Role of Copeptin in the Clinical Setting of Sepsis
المؤلفون المشاركون
Lupia, Enrico
Mengozzi, Giulio
Battista, Stefania
Audisio, Umberto
Galluzzo, Claudia
Maggiorotto, Matteo
Masoero, Monica
Forno, Daniela
Pizzolato, Elisa
Ulla, Marco
Lucchiari, Manuela
Vitale, Annarita
Moiraghi, Corrado
Settanni, Fabio
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The diagnostic and prognostic usefulness of copeptin were evaluated in septic patients, as compared to procalcitonin assessment.
In this single centre and observational study 105 patients were enrolled: 24 with sepsis, 25 with severe sepsis, 15 with septic shock, and 41 controls, divided in two subgroups (15 patients with gastrointestinal bleeding and 26 with suspected SIRS secondary to trauma, acute coronary syndrome, and pulmonary embolism).
Biomarkers were determined at the first medical evaluation and thereafter 24, 48, and 72 hours after admission.
Definitive diagnosis and in-hospital survival rates at 30 days were obtained through analysis of medical records.
At entry, copeptin proved to be able to distinguish cases from controls and also sepsis group from septic shock group, while procalcitonin could distinguish also severe sepsis from septic shock group.
Areas under the ROC curve for copeptin and procalcitonin were 0.845 and 0.861, respectively.
Noteworthy, patients with copeptin concentrations higher than the threshold value (23.2 pmol/L), calculated from the ROC curve, at admission presented higher 30-day mortality.
No significant differences were found in copeptin temporal profile among different subgroups.
Copeptin showed promising diagnostic and prognostic role in the management of sepsis, together with its possible role in monitoring the response to treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Battista, Stefania& Audisio, Umberto& Galluzzo, Claudia& Maggiorotto, Matteo& Masoero, Monica& Forno, Daniela…[et al.]. 2016. Assessment of Diagnostic and Prognostic Role of Copeptin in the Clinical Setting of Sepsis. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097385
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Battista, Stefania…[et al.]. Assessment of Diagnostic and Prognostic Role of Copeptin in the Clinical Setting of Sepsis. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097385
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Battista, Stefania& Audisio, Umberto& Galluzzo, Claudia& Maggiorotto, Matteo& Masoero, Monica& Forno, Daniela…[et al.]. Assessment of Diagnostic and Prognostic Role of Copeptin in the Clinical Setting of Sepsis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097385
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097385
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر