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Cementless Titanium Mesh Fixation of Osteoporotic Burst Fractures of the Lumbar Spine Leads to Bony Healing: Results of an Experimental Sheep Model
المؤلفون المشاركون
Mittlmeier, Thomas
Gradl, Georg
Vollmar, Brigitte
Roepenack, Paula
Roesner, Jan
Martin, Heiner
Reichel, Martin
Rotter, Robert
Herlyn, Philipp
Eschler, Anica
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-25
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
Current treatment strategies for osteoporotic vertebral compression fractures (VCFs) focus on cement-associated solutions.
Complications associated with cement application are leakage, embolism, adjacent fractures, and compromise in bony healing.
This study comprises a validated VCF model in osteoporotic sheep in order to (1) evaluate a new cementless fracture fixation technique using titanium mesh implants (TMIs) and (2) demonstrate the healing capabilities in osteoporotic VCFs.
Methods.
Twelve 5-year-old Merino sheep received ovariectomy, corticosteroid injections, and a calcium/phosphorus/vitamin D-deficient diet for osteoporosis induction.
Standardized VCFs (type AO A3.1) were created, reduced, and fixed using intravertebral TMIs.
Randomly additional autologous spongiosa grafting (G1) or no augmentation was performed (G2, n = 6 each).
Two months postoperatively, macroscopic, micro-CT and biomechanical evaluation assessed bony consolidation.
Results.
Fracture reduction succeeded in all cases without intraoperative complications.
Bony consolidation was proven for all cases with increased amounts of callus development for G2 (58.3%).
Micro-CT revealed cage integration.
Neither group showed improved results with biomechanical testing.
Conclusions.
Fracture reduction/fixation using TMIs without cement in osteoporotic sheep lumbar VCF resulted in bony fracture healing.
Intravertebral application of autologous spongiosa showed no beneficial effects.
The technique is now available for clinical use; thus, it offers an opportunity to abandon cement-associated complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Eschler, Anica& Roepenack, Paula& Roesner, Jan& Herlyn, Philipp& Martin, Heiner& Reichel, Martin…[et al.]. 2016. Cementless Titanium Mesh Fixation of Osteoporotic Burst Fractures of the Lumbar Spine Leads to Bony Healing: Results of an Experimental Sheep Model. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1097662
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Eschler, Anica…[et al.]. Cementless Titanium Mesh Fixation of Osteoporotic Burst Fractures of the Lumbar Spine Leads to Bony Healing: Results of an Experimental Sheep Model. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1097662
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Eschler, Anica& Roepenack, Paula& Roesner, Jan& Herlyn, Philipp& Martin, Heiner& Reichel, Martin…[et al.]. Cementless Titanium Mesh Fixation of Osteoporotic Burst Fractures of the Lumbar Spine Leads to Bony Healing: Results of an Experimental Sheep Model. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1097662
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097662
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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