Effects of Lycium barbarum Polysaccharides on Apoptosis, Cellular Adhesion, and Oxidative Damage in Bone Marrow Mononuclear Cells of Mice Exposed to Ionizing Radiation Injury
المؤلفون المشاركون
Zhou, Jing
Pang, Hua
Li, Wenbo
Liu, Qiong
Xu, Lu
Liu, Qian
Liu, Ying
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Lycium barbarum has been used for more than 2500 years as a traditional herb and food in China.
We investigated the effects of Lycium barbarum polysaccharides (LBP) on apoptosis, oxidative damage, and expression of adhesion molecules in bone marrow mononuclear cells (BMNC) of mice injured by ionizing radiation.
Kunming mice were exposed to X-rays; then mice in the LBP groups were continuously injected with various concentrations of LBP intraperitoneally for 14 days.
Mice in the control group were continuously injected with normal saline (NS) by the same route for 14 days.
A normal group was set up.
After 1, 7, and 14 days of treatment, mice were killed and BMNC were extracted.
Cell cycle, apoptosis, and the expression of adhesion molecules CD44 and CD49d were detected by flow cytometry.
The levels of malondialdehyde (MDA) and superoxide dismutase (SOD) were identified by colorimetric analyses.
LBP significantly decreased the percentage of G0/G1 phase, apoptosis, MDA level, and expression of CD44 and CD49d and distinctly increased the activity of SOD.
LBP showed a protective effect on BMNC against ionizing radiation-induced apoptosis and oxidative damage and altered the expression of adhesion molecule.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Jing& Pang, Hua& Li, Wenbo& Liu, Qiong& Xu, Lu& Liu, Qian…[et al.]. 2016. Effects of Lycium barbarum Polysaccharides on Apoptosis, Cellular Adhesion, and Oxidative Damage in Bone Marrow Mononuclear Cells of Mice Exposed to Ionizing Radiation Injury. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097678
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Jing…[et al.]. Effects of Lycium barbarum Polysaccharides on Apoptosis, Cellular Adhesion, and Oxidative Damage in Bone Marrow Mononuclear Cells of Mice Exposed to Ionizing Radiation Injury. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1097678
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Jing& Pang, Hua& Li, Wenbo& Liu, Qiong& Xu, Lu& Liu, Qian…[et al.]. Effects of Lycium barbarum Polysaccharides on Apoptosis, Cellular Adhesion, and Oxidative Damage in Bone Marrow Mononuclear Cells of Mice Exposed to Ionizing Radiation Injury. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097678
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097678
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر