Effect of LongZhang Gargle on Biofilm Formation and Acidogenicity of Streptococcus mutans In Vitro
المؤلفون المشاركون
Yang, Yutao
Liu, Shiyu
He, Yuanli
Chen, Zhu
Li, Mingyun
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Streptococcus mutans, with the ability of high-rate acid production and strong biofilm formation, is considered the predominant bacterial species in the pathogenesis of human dental caries.
Natural products which may be bioactive against S.
mutans have become a hot spot to researches to control dental caries.
LongZhang Gargle, completely made from Chinese herbs, was investigated for its effects on acid production and biofilm formation by S.
mutans in this study.
The results showed an antimicrobial activity of LongZhang Gargle against S.
mutans planktonic growth at the minimum inhibitory concentration (MIC) of 16% and minimum bactericidal concentration (MBC) of 32%.
Acid production was significantly inhibited at sub-MIC concentrations.
Biofilm formation was also significantly disrupted, and 8% was the minimum concentration that resulted in at least 50% inhibition of biofilm formation (MBIC50).
A scanning electron microscopy (SEM) showed an effective disruption of LongZhang Gargle on S.
mutans biofilm integrity.
In addition, a confocal laser scanning microscopy (CLSM) suggested that the extracellular polysaccharides (EPS) synthesis could be inhibited by LongZhang Gargle at a relatively low concentration.
These findings suggest that LongZhang Gargle may be a promising natural anticariogenic agent in that it suppresses planktonic growth, acid production, and biofilm formation against S.
mutans.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Yutao& Liu, Shiyu& He, Yuanli& Chen, Zhu& Li, Mingyun. 2016. Effect of LongZhang Gargle on Biofilm Formation and Acidogenicity of Streptococcus mutans In Vitro. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098229
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Yutao…[et al.]. Effect of LongZhang Gargle on Biofilm Formation and Acidogenicity of Streptococcus mutans In Vitro. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098229
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Yutao& Liu, Shiyu& He, Yuanli& Chen, Zhu& Li, Mingyun. Effect of LongZhang Gargle on Biofilm Formation and Acidogenicity of Streptococcus mutans In Vitro. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098229
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098229
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر