The Effect of Advanced Motherhood on Newborn Offspring’s Hippocampal Neural Stem Cell Proliferation
المؤلفون المشاركون
Li, Bo
Duan, Ping
Han, Xuefei
Yan, Wenhai
Xing, Ying
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the effect of advanced motherhood on rat hippocampal neural stem cell proliferation.
Methods.
Female parents were subdivided into control and old mother group by age, and neural stem cells were cultured from hippocampal tissues for 24 h newborn offspring.
The diameter and numbers of neurospheres were examined by microscopy, and differences in proliferation were examined by EdU immunofluorescence, CCK-8 assay, and cell cycle analysis.
Results.
The number of neurospheres in the old mother group after culture was lower than the control group.
Additionally, neurospheres’ diameter was smaller than that of the control group (P<0.05).
The EdU positive rate of the old mother group was lower than that of the control group (P<0.05).
CCK-8 assay results showed that the absorbance values for the old mother group were lower than that of the control group at 48 h and 72 h (P<0.05).
The proportions of cells in the S and G2/M phases of the cell cycle for the older mother group were less than that found for the control group (P<0.05).
Conclusion.
The proliferation rates of hippocampal NSCs seen in the older mother group were lower than that seen in the control group.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Bo& Duan, Ping& Han, Xuefei& Yan, Wenhai& Xing, Ying. 2016. The Effect of Advanced Motherhood on Newborn Offspring’s Hippocampal Neural Stem Cell Proliferation. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098401
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Bo…[et al.]. The Effect of Advanced Motherhood on Newborn Offspring’s Hippocampal Neural Stem Cell Proliferation. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098401
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Bo& Duan, Ping& Han, Xuefei& Yan, Wenhai& Xing, Ying. The Effect of Advanced Motherhood on Newborn Offspring’s Hippocampal Neural Stem Cell Proliferation. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098401
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098401
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر