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Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats
المؤلفون المشاركون
Karim, Nurul
Afroz, Rizwana
Tanvir, E. M.
Khalil, Md. Ibrahim
Alam, Nadia
Hossain, M. Sabir
Gan, Siew Hua
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction.
Adult male Wistar Albino rats were pretreated with Sundarban honey (5 g/kg) daily for a period of 6 weeks.
After the treatment period, ISO (85 mg/kg) was subcutaneously injected into the rats at 24 h intervals for 2 days.
ISO-induced myocardial damage was indicated by increased serum cardiac specific troponin I levels and cardiac marker enzyme activities including creatine kinase-MB, lactate dehydrogenase, aspartate transaminase, and alanine transaminase.
Significant increases in serum total cholesterol, triglycerides, and low-density lipoprotein-cholesterol levels were also observed, along with a reduction in the serum high-density lipoprotein-cholesterol level.
In addition to these diagnostic markers, the levels of lipid peroxide products were significantly increased.
The activities of antioxidant enzymes such as superoxide dismutase, glutathione peroxidase, and glutathione reductase were significantly decreased in the hearts after ISO-induced myocardial infarction.
However, pretreatment of ischemic rats with Sundarban honey brought the biochemical parameters to near normalcy, indicating the protective effect of Sundarban honey against ISO-induced ischemia in rats.
Histopathological findings of the heart tissues further confirmed the biochemical findings, indicating that Sundarban honey confers protection against ISO-induced oxidative stress in the myocardium.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Afroz, Rizwana& Tanvir, E. M.& Karim, Nurul& Hossain, M. Sabir& Alam, Nadia& Gan, Siew Hua…[et al.]. 2016. Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098478
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Afroz, Rizwana…[et al.]. Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098478
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Afroz, Rizwana& Tanvir, E. M.& Karim, Nurul& Hossain, M. Sabir& Alam, Nadia& Gan, Siew Hua…[et al.]. Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098478
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098478
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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