Remote Postconditioning Alone and Combined with Hypothermia Improved Postresuscitation Cardiac and Neurological Outcomes in Swine
المؤلفون المشاركون
Xu, Jiefeng
Huang, Zeng
Ye, Sen
Wang, Moli
Fang, Ya
Li, Zilong
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
Previously, we demonstrated that remote ischemic postconditioning (RIpostC) improved postresuscitation myocardial and cerebral functions in rat.
Here, we investigated the effects of RIpostC alone and combined with therapeutic hypothermia (TH) on cardiac and neurological outcomes after CPR in swine.
Methods.
Twenty-one pigs were subjected to 10 mins of VF and then 5 mins of CPR.
The animals were randomized to receive RIpostC alone, or its combination with TH, or sham control.
RIpostC was induced by 4 cycles of limb ischemia followed by reperfusion.
TH was implemented by surface cooling to reach a temperature of 32–34°C.
Results.
During 72 hrs after resuscitation, lower level of cardiac troponin I and greater stroke volume and global ejection fraction were observed in animals that received RIpostC when compared to the control.
RIpostC also decreased serum levels of neuron-specific enolase and S100B and increased neurologic alertness score after resuscitation.
The combination of RIpostC and TH resulted in greater improvement in cardiac and neurological outcomes than RIpostC alone.
Conclusion.
RIpostC was conducive to improving postresuscitation myocardial and cerebral functions and reducing their organ injuries.
Its combination with TH further enhanced its protective effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Jiefeng& Huang, Zeng& Ye, Sen& Wang, Moli& Fang, Ya& Li, Zilong. 2016. Remote Postconditioning Alone and Combined with Hypothermia Improved Postresuscitation Cardiac and Neurological Outcomes in Swine. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098539
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Jiefeng…[et al.]. Remote Postconditioning Alone and Combined with Hypothermia Improved Postresuscitation Cardiac and Neurological Outcomes in Swine. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098539
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Jiefeng& Huang, Zeng& Ye, Sen& Wang, Moli& Fang, Ya& Li, Zilong. Remote Postconditioning Alone and Combined with Hypothermia Improved Postresuscitation Cardiac and Neurological Outcomes in Swine. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098539
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098539
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر