Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s)‎ in a Mass Colorectal Cancer Screening

المؤلفون المشاركون

Cai, Shan-Rong
Zhu, Hong-Hong
Huang, Yan-Qin
Li, Qi-Long
Ma, Xin-Yuan
Zhang, Su-Zhan
Zheng, Shu

المصدر

BioMed Research International

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-04-07

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الطب البشري

الملخص EN

This study investigated the cost-effectiveness between double and single Fecal Immunochemical Test(s) (FIT) in a mass CRC screening.

A two-stage sequential screening was conducted.

FIT was used as a primary screening test and recommended twice by an interval of one week at the first screening stage.

We defined the first-time FIT as FIT1 and the second-time FIT as FIT2.

If either FIT1 or FIT2 was positive (+), then a colonoscopy was recommended at the second stage.

Costs were recorded and analyzed.

A total of 24,419 participants completed either FIT1 or FIT2.

The detection rate of advanced neoplasm was 19.2% among both FIT1+ and FIT2+, especially high among men with age ≥55 (27.4%).

About 15.4% CRC, 18.9% advanced neoplasm, and 29.9% adenoma missed by FIT1 were detected by FIT2 alone.

Average cost was $2,935 for double FITs and $2,121 for FIT1 to detect each CRC and $901 for double FITs and $680 for FIT1 to detect each advanced neoplasm.

Double FITs are overall more cost-effective, having significantly higher positive and detection rates with an acceptable higher cost, than single FIT.

Double FITs should be encouraged for the first screening in a mass CRC screening, especially in economically and medically underserved populations/areas/countries.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Cai, Shan-Rong& Zhu, Hong-Hong& Huang, Yan-Qin& Li, Qi-Long& Ma, Xin-Yuan& Zhang, Su-Zhan…[et al.]. 2016. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098607

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Cai, Shan-Rong…[et al.]. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1098607

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Cai, Shan-Rong& Zhu, Hong-Hong& Huang, Yan-Qin& Li, Qi-Long& Ma, Xin-Yuan& Zhang, Su-Zhan…[et al.]. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098607

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1098607