Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening
Joint Authors
Cai, Shan-Rong
Zhu, Hong-Hong
Huang, Yan-Qin
Li, Qi-Long
Ma, Xin-Yuan
Zhang, Su-Zhan
Zheng, Shu
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This study investigated the cost-effectiveness between double and single Fecal Immunochemical Test(s) (FIT) in a mass CRC screening.
A two-stage sequential screening was conducted.
FIT was used as a primary screening test and recommended twice by an interval of one week at the first screening stage.
We defined the first-time FIT as FIT1 and the second-time FIT as FIT2.
If either FIT1 or FIT2 was positive (+), then a colonoscopy was recommended at the second stage.
Costs were recorded and analyzed.
A total of 24,419 participants completed either FIT1 or FIT2.
The detection rate of advanced neoplasm was 19.2% among both FIT1+ and FIT2+, especially high among men with age ≥55 (27.4%).
About 15.4% CRC, 18.9% advanced neoplasm, and 29.9% adenoma missed by FIT1 were detected by FIT2 alone.
Average cost was $2,935 for double FITs and $2,121 for FIT1 to detect each CRC and $901 for double FITs and $680 for FIT1 to detect each advanced neoplasm.
Double FITs are overall more cost-effective, having significantly higher positive and detection rates with an acceptable higher cost, than single FIT.
Double FITs should be encouraged for the first screening in a mass CRC screening, especially in economically and medically underserved populations/areas/countries.
American Psychological Association (APA)
Cai, Shan-Rong& Zhu, Hong-Hong& Huang, Yan-Qin& Li, Qi-Long& Ma, Xin-Yuan& Zhang, Su-Zhan…[et al.]. 2016. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098607
Modern Language Association (MLA)
Cai, Shan-Rong…[et al.]. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1098607
American Medical Association (AMA)
Cai, Shan-Rong& Zhu, Hong-Hong& Huang, Yan-Qin& Li, Qi-Long& Ma, Xin-Yuan& Zhang, Su-Zhan…[et al.]. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098607
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098607