The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis
المؤلفون المشاركون
Ubaldi, Filippo
Cimadomo, Danilo
Capalbo, Antonio
Scarica, Catello
Palagiano, Antonio
Canipari, Rita
Rienzi, Laura
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-28
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Preimplantation Genetic Diagnosis and Screening (PGD/PGS) for monogenic diseases and/or numerical/structural chromosomal abnormalities is a tool for embryo testing aimed at identifying nonaffected and/or euploid embryos in a cohort produced during an IVF cycle.
A critical aspect of this technology is the potential detrimental effect that the biopsy itself can have upon the embryo.
Different embryo biopsy strategies have been proposed.
Cleavage stage blastomere biopsy still represents the most commonly used method in Europe nowadays, although this approach has been shown to have a negative impact on embryo viability and implantation potential.
Polar body biopsy has been proposed as an alternative to embryo biopsy especially for aneuploidy testing.
However, to date no sufficiently powered study has clarified the impact of this procedure on embryo reproductive competence.
Blastocyst stage biopsy represents nowadays the safest approach not to impact embryo implantation potential.
For this reason, as well as for the evidences of a higher consistency of the molecular analysis when performed on trophectoderm cells, blastocyst biopsy implementation is gradually increasing worldwide.
The aim of this review is to present the evidences published to date on the impact of the biopsy at different stages of preimplantation development upon human embryos reproductive potential.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cimadomo, Danilo& Capalbo, Antonio& Ubaldi, Filippo& Scarica, Catello& Palagiano, Antonio& Canipari, Rita…[et al.]. 2016. The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098739
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cimadomo, Danilo…[et al.]. The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098739
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cimadomo, Danilo& Capalbo, Antonio& Ubaldi, Filippo& Scarica, Catello& Palagiano, Antonio& Canipari, Rita…[et al.]. The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098739
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098739
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر