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Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence
المؤلفون المشاركون
Nakagawa, Hiroshi
Toyoda, Yu
Gomi, Tsuneaki
Nagakura, Makoto
Ishikawa, Toshihisa
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-23
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The importance of personalized medicine and healthcare is becoming increasingly recognized.
Genetic polymorphisms associated with potential risks of various human genetic diseases as well as drug-induced adverse reactions have recently been well studied, and their underlying molecular mechanisms are being uncovered by functional genomics as well as genome-wide association studies.
Knowledge of certain genetic polymorphisms is clinically important for our understanding of interindividual differences in drug response and/or disease risk.
As such evidence accumulates, new clinical applications and practices are needed.
In this context, the development of new technologies for simple, fast, accurate, and cost-effective genotyping is imperative.
Here, we describe a simple isothermal genotyping method capable of detecting single nucleotide polymorphisms (SNPs) in the human ATP-binding cassette (ABC) transporter ABCC11 gene and its application to the clinical diagnosis of axillary osmidrosis.
We have recently reported that axillary osmidrosis is linked with one SNP 538G>A in the ABCC11 gene.
Our molecular biological and biochemical studies have revealed that this SNP greatly affects the protein expression level and the function of ABCC11.
In this review, we highlight the clinical relevance and importance of this diagnostic strategy in axillary osmidrosis therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Toyoda, Yu& Gomi, Tsuneaki& Nakagawa, Hiroshi& Nagakura, Makoto& Ishikawa, Toshihisa. 2016. Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098847
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Toyoda, Yu…[et al.]. Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1098847
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Toyoda, Yu& Gomi, Tsuneaki& Nakagawa, Hiroshi& Nagakura, Makoto& Ishikawa, Toshihisa. Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098847
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098847
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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