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Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada
المؤلفون المشاركون
Burak, Kelly W.
Meeberg, Glenda A.
Myers, Robert P.
Fick, Gordon H.
Swain, Mark G.
Bain, Vincent G.
Kneteman, Norman M.
Hilsden, Robert J.
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-03
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Since 2002, the Model of End-Stage Liver Disease (MELD) has been used for allocation of liver transplants (LT) in the USA.
In Canada, livers were allocated by the CanWAIT algorithm.
The aim of this study was to compare the abilities of MELD, Child-Pugh (CP), and CanWAIT status to predict 3-month and 1-year mortality before LT in Canadian patients and to describe the use of MELD in Canada.
Methods.
Validation of MELD was performed in 320 patients listed for LT in Alberta (1998–2002).
In October 2014, a survey of MELD use by Canadian LT centers was conducted.
Results.
Within 1 year of listing, 47 patients were removed from the waiting list (29 deaths, 18 too ill for LT).
Using logistic regression, the MELD and CP were better than the CanWAIT at predicting 3-month (AUROC: 0.79, 0.78, and 0.59; p = 0.0002 ) and 1-year waitlist mortality (AUROC: 0.70, 0.70, and 0.55; p = 0.0023 ).
Beginning in 2004, MELD began to be adopted by Canadian LT programs but its use was not standardized.
Conclusions.
Compared with the CanWAIT system, the MELD score was significantly better at predicting LT waitlist mortality.
MELD-sodium (MELD-Na) has now been adopted for LT allocation in Canada.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Burak, Kelly W.& Meeberg, Glenda A.& Myers, Robert P.& Fick, Gordon H.& Swain, Mark G.& Bain, Vincent G.…[et al.]. 2016. Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099836
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Burak, Kelly W.…[et al.]. Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1099836
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Burak, Kelly W.& Meeberg, Glenda A.& Myers, Robert P.& Fick, Gordon H.& Swain, Mark G.& Bain, Vincent G.…[et al.]. Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099836
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099836
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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