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Human Papilloma Virus Persistence after Cone Excision in Women with Cervical High Grade Squamous Intraepithelial Lesion: A Prospective Study
المؤلفون المشاركون
Pirtea, Laurențiu
Grigoraş, Dorin
Matusz, Petru
Pirtea, Marilena
Moleriu, Lavinia
Tudor, Anca
Ilina, Răzvan
Secoşan, Cristina
Horhat, Florin
Mazilu, Octavian
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-12
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Persistent human papillomavirus (HPV) infection is a necessary event in cervical cancer tumorigenesis.
Our objectives were to estimate the rate of HPV infection persistence after large loop excision of the transformation zone (LEEP) in patients with high grade squamous intraepithelial lesions (HSIL) and to investigate if HPV persistence is type related.
Methods.
We conducted a prospective study on 89 patients with HSIL treated with LEEP.
DNA HPV was performed before surgery and at 6, 12, and 18 months after LEEP.
Results.
Four patients were excluded from the study.
The HPV persistence in the remaining 85 patients was 32.95% (6 months), 14.12% (12 months), and 10.59% (18 months).
Type 16 had the highest persistence rate, 23.5% (6 months), 11.8% (12 months), and 8.2% (18 months).
Coinfection was found to be 54.12% before LEEP and 18.8% (6 months), 4.7% (12 months), and 3.5% (18 months) after LEEP.
The rate of coinfections including type 16 was 46.83% of all coinfections.
Coinfection including type 16 was not correlated with higher persistence rate compared to infection with type 16 only.
Conclusions.
HPV infection is not completely eradicated by LEEP in patients with HSIL lesion on PAP smear.
HPV persistence after LEEP is influenced by HPV type.
HPV type 16 has the highest persistence rate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pirtea, Laurențiu& Grigoraş, Dorin& Matusz, Petru& Pirtea, Marilena& Moleriu, Lavinia& Tudor, Anca…[et al.]. 2016. Human Papilloma Virus Persistence after Cone Excision in Women with Cervical High Grade Squamous Intraepithelial Lesion: A Prospective Study. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099981
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pirtea, Laurențiu…[et al.]. Human Papilloma Virus Persistence after Cone Excision in Women with Cervical High Grade Squamous Intraepithelial Lesion: A Prospective Study. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1099981
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pirtea, Laurențiu& Grigoraş, Dorin& Matusz, Petru& Pirtea, Marilena& Moleriu, Lavinia& Tudor, Anca…[et al.]. Human Papilloma Virus Persistence after Cone Excision in Women with Cervical High Grade Squamous Intraepithelial Lesion: A Prospective Study. Canadian Journal of Infectious Diseases and Medical Microbiology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099981
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099981
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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