Antibiotic Utilization Patterns in Patients with Ventilator-Associated Pneumonia: A Canadian Context
المؤلفون المشاركون
Chin, Tracy
Kushner, Barry
Dersch-Mills, Deonne
Zuege, Danny J.
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-20
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This retrospective cohort study describes the patterns of antibiotic use for the treatment of ventilator-associated pneumonia (VAP) in the Calgary Zone of Alberta Health Services.
Timing, appropriateness, and duration of antibiotics were evaluated in two hundred consecutive cases of VAP derived from 4 adult intensive care units (ICU).
Antibiotic therapy was initiated in less than 24 hours from VAP diagnosis in 83% of cases.
Although most patients (89%) received empiric therapy that demonstrated in vitro sensitivity to the identified pathogens, only 24% of cases were congruent with the 2008 Association of Medical Microbiology and Infectious Disease (AMMI) guidelines.
Both ICU ( p = 0.001 ) and hospital ( p = 0.015 ) mortality were significantly lower and there was a trend for shorter ICU length of stay ( p = 0.051 ) in patients who received appropriate versus inappropriate initial antibiotics.
There were no outcome differences related to compliance with AMMI guidelines.
This exploratory study provides insight into the use of antimicrobials for the treatment of VAP in a large Canadian health region.
The discordance between the assessments of appropriateness of empiric therapy based on recovered pathogens versus AMMI guidelines is notable, emphasizing the importance of using as much as possible local microbiologic and antimicrobial resistance data.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chin, Tracy& Kushner, Barry& Dersch-Mills, Deonne& Zuege, Danny J.. 2016. Antibiotic Utilization Patterns in Patients with Ventilator-Associated Pneumonia: A Canadian Context. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1099986
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chin, Tracy…[et al.]. Antibiotic Utilization Patterns in Patients with Ventilator-Associated Pneumonia: A Canadian Context. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1099986
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chin, Tracy& Kushner, Barry& Dersch-Mills, Deonne& Zuege, Danny J.. Antibiotic Utilization Patterns in Patients with Ventilator-Associated Pneumonia: A Canadian Context. Canadian Journal of Infectious Diseases and Medical Microbiology. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1099986
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099986
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر