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Clival Ectopic Pituitary Adenoma Mimicking a Chordoma: Case Report and Review of the Literature
المؤلفون المشاركون
Bendok, B. R.
Karras, Constantine L.
Abecassis, Isaac Josh
Abecassis, Zachary A.
Adel, Joseph G.
Bit-Ivan, Esther N.
Chandra, Rakesh K.
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-13
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Purely ectopic pituitary adenomas are exceedingly rare.
Here we report on a patient that presented with an incidental clival mass thought to be a chordoma.
Endonasal resection, tumor pathology, and endocrinology workup revealed a prolactinoma.
Case Presentation.
A 41-year-old male presented with an incidental clival lesion presumed to be a chordoma.
On MRI it involved the entire clivus, extended laterally to the petroclival junction, and invaded the cavernous sinuses bilaterally, encasing both internal carotid arteries, without direct extension into the sella.
Intraoperatively, it was clear that the tumor originated from the clivus and that the sellar dura was completely intact.
Frozen-section pathology was consistent with a pituitary adenoma.
Immunostaining was positive for synaptophysin and prolactin with a low Ki-67 index, suggestive of a prolactinoma.
Additional immunohistochemical stains seen in chordomas (EMA, S100, and Brachyury) and other metastatic tumors were negative.
A postoperative endocrine workup revealed an elevated serum prolactin of 881.3 ng/mL (normal < 20).
Conclusions.
In conclusion, it is crucial to maintain an extensive differential diagnosis when evaluating a patient with a clival lesion.
Ectopic clival pituitary adenomas, although rare, may warrant an endocrinological workup preoperatively as the majority may respond to medical treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Karras, Constantine L. & Abecassis, Isaac Josh & Abecassis, Zachary A.& Adel, Joseph G.& Bit-Ivan, Esther N. & Chandra, Rakesh K.…[et al.]. 2016. Clival Ectopic Pituitary Adenoma Mimicking a Chordoma: Case Report and Review of the Literature. Case Reports in Neurological Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1101325
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Karras, Constantine L.…[et al.]. Clival Ectopic Pituitary Adenoma Mimicking a Chordoma: Case Report and Review of the Literature. Case Reports in Neurological Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1101325
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Karras, Constantine L. & Abecassis, Isaac Josh & Abecassis, Zachary A.& Adel, Joseph G.& Bit-Ivan, Esther N. & Chandra, Rakesh K.…[et al.]. Clival Ectopic Pituitary Adenoma Mimicking a Chordoma: Case Report and Review of the Literature. Case Reports in Neurological Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1101325
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1101325
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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