Safety and Efficacy of Intrapleural Tissue Plasminogen Activator and DNase during Extended Use in Complicated Pleural Space Infections
المؤلفون المشاركون
McClune, Jason R.
Wilshire, Candice L.
Gorden, Jed A.
Louie, Brian E.
Farviar, Alexander S.
Stefanski, Michael J.
Vallieres, Eric
Aye, Ralph W.
Gilbert, Christopher R.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The use of intrapleural therapy with tissue plasminogen activator and DNase improves outcomes in patients with complicated pleural space infections.
However, little data exists for the use of combination intrapleural therapy after the initial dosing period of six doses.
We sought to describe the safety profile and outcomes of intrapleural therapy beyond this standard dosing.
A retrospective review of patients receiving intrapleural therapy with tissue plasminogen activator and DNase was performed at two institutions.
We identified 101 patients from January 2013 to August 2015 receiving intrapleural therapy for complicated pleural space infection.
The extended use of intrapleural tissue plasminogen activator and DNase therapy beyond six doses was utilized in 20% (20/101) of patients.
The mean number of doses in those undergoing extended dosing was 9.8 (range of 7–16).
Within the population studied there appears to be no statistically significant increased risk of complications, need for surgical referral, or outcome differences when comparing those receiving standard or extended dosing intrapleural therapy.
Future prospective study of intrapleural therapy as an alternative option for patients who fail initial pleural drainage and are unable to tolerate/accept a surgical intervention appears a potential area of study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
McClune, Jason R.& Wilshire, Candice L.& Gorden, Jed A.& Louie, Brian E.& Farviar, Alexander S.& Stefanski, Michael J.…[et al.]. 2016. Safety and Efficacy of Intrapleural Tissue Plasminogen Activator and DNase during Extended Use in Complicated Pleural Space Infections. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103268
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
McClune, Jason R.…[et al.]. Safety and Efficacy of Intrapleural Tissue Plasminogen Activator and DNase during Extended Use in Complicated Pleural Space Infections. Canadian Respiratory Journal No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103268
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
McClune, Jason R.& Wilshire, Candice L.& Gorden, Jed A.& Louie, Brian E.& Farviar, Alexander S.& Stefanski, Michael J.…[et al.]. Safety and Efficacy of Intrapleural Tissue Plasminogen Activator and DNase during Extended Use in Complicated Pleural Space Infections. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103268
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103268
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر