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Role of Neutrophil Gelatinase-Associated Lipocalin in the Diagnosis and Early Treatment of Acute Kidney Injury in a Case Series of Patients with Acute Decompensated Heart Failure: A Case Series
المؤلفون المشاركون
Angeletti, Silvia
Lo Presti, Alessandra
Dicuonzo, Giordano
De Cesaris, Marina
Fogolari, Marta
Ciccozzi, Massimo
Morolla, Davide
Capone, Federico
Costantino, Sebastiano
Spoto, Silvia
المصدر
Cardiology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Patients with acute decompensated heart failure (ADHF) frequently develop worsening in renal function until Acute Kidney Injury (AKI).
The use of kidney injury biomarkers could be useful in the early diagnosis of AKI.
In the present study, the role of the neutrophil gelatinase-associated lipocalin (NGAL), compared to the standard creatinine, in ADHF patients, was analyzed to evaluate if an early treatment could affect the outcome.
A case series of 24 ADHF patients was enrolled and patients randomly divided in two groups (Group A and Group B).
In Group A, NGAL, creatinine, and eGFR were measured, while in Group B, creatinine and eGFR alone were measured.
NGAL was measured by turbidimetric immunoassay and creatinine using an enzymatic spectrophotometric method.
In presence of AKI, creatinine increase and eGFR decrease were significantly lower in Group A than in Group B, whereas in absence of AKI the difference between the two groups was not significant.
Hospitalization stay was significantly lower in Group A (receiving early treatment based on NGAL) than in Group B.
In ADHF patients, plasma NGAL in combination with creatinine was superior to the standard creatinine in the diagnosis and early treatment of AKI with a better outcome and a decreased hospital stay.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Angeletti, Silvia& Fogolari, Marta& Morolla, Davide& Capone, Federico& Costantino, Sebastiano& Spoto, Silvia…[et al.]. 2016. Role of Neutrophil Gelatinase-Associated Lipocalin in the Diagnosis and Early Treatment of Acute Kidney Injury in a Case Series of Patients with Acute Decompensated Heart Failure: A Case Series. Cardiology Research and Practice،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103281
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Angeletti, Silvia…[et al.]. Role of Neutrophil Gelatinase-Associated Lipocalin in the Diagnosis and Early Treatment of Acute Kidney Injury in a Case Series of Patients with Acute Decompensated Heart Failure: A Case Series. Cardiology Research and Practice No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103281
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Angeletti, Silvia& Fogolari, Marta& Morolla, Davide& Capone, Federico& Costantino, Sebastiano& Spoto, Silvia…[et al.]. Role of Neutrophil Gelatinase-Associated Lipocalin in the Diagnosis and Early Treatment of Acute Kidney Injury in a Case Series of Patients with Acute Decompensated Heart Failure: A Case Series. Cardiology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103281
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103281
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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