Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients
المؤلفون المشاركون
Koch, Alexander
Benz, Fabian
Roderburg, Christoph
Luedde, Mark
Niedeggen, Jennifer
Vucur, Mihael
Hippe, Hans-Joerg
Spehlmann, Martina E.
Schueller, Florian
Loosen, Sven
Frey, Norbert
Luedde, Tom
Trautwein, Christian
Tacke, Frank
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
Omentin, a recently described adipokine, was shown to be involved in the pathophysiology of inflammatory and infectious diseases.
However, its role in critical illness and sepsis is currently unknown.
Materials and Methods.
Omentin serum concentrations were measured in 117 ICU-patients (84 with septic and 33 with nonseptic disease etiology) admitted to the medical ICU.
Results were compared with 50 healthy controls.
Results.
Omentin serum levels of critically ill patients at admission to the ICU or after 72 hours of ICU treatment were similar compared to healthy controls.
Moreover, circulating omentin levels were independent of sepsis and etiology of critical illness.
Notably, serum concentrations of omentin could not be linked to concentrations of inflammatory cytokines or routinely used sepsis markers.
While serum levels of omentin were not predictive for short term survival during ICU treatment, low omentin concentrations were an independent predictor of patients’ overall survival.
Omentin levels strongly correlated with that of other adipokines (e.g., leptin receptor or adiponectin), which have also been identified as prognostic markers in critical illness.
Conclusions.
Although circulating omentin levels did not differ between ICU-patients and controls, elevated omentin levels were predictive for an impaired patients’ long term survival.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luedde, Mark& Benz, Fabian& Niedeggen, Jennifer& Vucur, Mihael& Hippe, Hans-Joerg& Spehlmann, Martina E.…[et al.]. 2016. Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients. Disease Markers،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103681
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luedde, Mark…[et al.]. Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients. Disease Markers No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103681
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luedde, Mark& Benz, Fabian& Niedeggen, Jennifer& Vucur, Mihael& Hippe, Hans-Joerg& Spehlmann, Martina E.…[et al.]. Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103681
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103681
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر