Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure
المؤلفون المشاركون
Huang, Ying
Chang, Chao
Zhang, Shumin
Wang, Zhijian
Zhang, Jianwei
Liu, Ling
Liu, Xiaofei
Lin, Ying-zhong
Ji, Qing-wei
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-24
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Recent evidence demonstrated that the circulating levels of omentin-1 are related to the presence of ischemic heart disease and heart failure.
However, omentin-1 plasma levels in patients with nonischemic dilated cardiomyopathy (DCM), which is the most common etiology of heart failure, have yet to be investigated.
Methods.
Plasma levels of omentin-1 and adiponectin were measured in 100 patients with DCM and 45 healthy controls.
Results.
Plasma omentin-1 levels significantly decreased in DCM patients compared with the control group, whereas adiponectin levels significantly increased in DCM patients compared with the control group.
Plasma omentin-1 levels were negatively correlated with adiponectin ( R = - 0.376 , P = 0.005 ), C-reactive protein (CRP) ( R = - 0.320 , P = 0.001 ), and N-terminal pro-brain natriuretic peptide (NT-proBNP) ( R = - 0.365 , P = 0.000 ) levels as well as left ventricular end-diastolic diameter (LVEDD) ( R = - 0.200 , P = 0.046 ) but were positively correlated with left ventricular ejection fraction (LVEF) ( R = 0.496 , P = 0.000 ).
Plasma adiponectin levels were positively correlated with CRP ( R = 0.273 , P = 0.006 ) and NT-proBNP ( R = 0.329 , P = 0.001 ) levels but were negatively correlated with fasting glucose ( R = - 0.218 , P = 0.029 ) and LVEF ( R = - 0.615 , P = 0.000 ) levels.
Furthermore, omentin-1 (OR 0.983, 95% CI 0.970 to 0.996; P = 0.008 ) levels were independently associated with the presence of DCM before NT-proBNP was added.
Conclusions.
Omentin-1 is a novel biomarker of DCM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Ying& Lin, Ying-zhong& Zhang, Shumin& Wang, Zhijian& Zhang, Jianwei& Chang, Chao…[et al.]. 2016. Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure. Disease Markers،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103743
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Ying…[et al.]. Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure. Disease Markers No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103743
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Ying& Lin, Ying-zhong& Zhang, Shumin& Wang, Zhijian& Zhang, Jianwei& Chang, Chao…[et al.]. Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103743
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103743
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر