Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses
المؤلفون المشاركون
Zhou, Qiaozhen
Zhu, Li
Zhang, Dafeng
Li, Ning
Li, Qiao
Dai, Panpan
Mao, Yixin
Li, Xumin
Ma, Jianfeng
Huang, Shengbin
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-10
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Numerous studies suggested that oxidative stress (OS) played a central role in the onset and development of postmenopausal osteoporosis (PO); however, conflicting results were obtained as to the association of OS-related biomarkers and PO.
This meta-analysis aimed to identify the association between these markers and PO, and explore factors that may explain the inconsistencies in these results.
A systematic literature search was conducted in relevant database.
Search terms and selection criteria were priorly determined to identify and include all studies that detected markers of OS in PO patients.
We pooled data with a random effects meta-analysis with standardized mean differences and 95% confidence interval.
Total 17 studies including 12 OS markers were adopted.
The results showed that superoxide dismutase (SOD) in erythrocytes, catalase (CAT), total antioxidant status (TAS), hydroperoxides (HY), advanced oxidation protein products (AOPP), malondialdehyde (MDA), and vitamin B12 (VB12) in plasma/serum were not statistically different between the PO and control group, whereas significantly increased level of homocysteine (Hcy) and nitric oxide (NO), along with decreased SOD, glutathione peroxidase (GPx), folate, and total antioxidant power (TAP) in plasma/serum were obtained in the PO group.
In summary, OS might serve as potential biomarkers in the etiopathophysiology and clinical course of PO.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Qiaozhen& Zhu, Li& Zhang, Dafeng& Li, Ning& Li, Qiao& Dai, Panpan…[et al.]. 2016. Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses. Disease Markers،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1103751
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Qiaozhen…[et al.]. Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses. Disease Markers No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1103751
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Qiaozhen& Zhu, Li& Zhang, Dafeng& Li, Ning& Li, Qiao& Dai, Panpan…[et al.]. Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1103751
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103751
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر