Galectin-3 Reflects Mitral Annular Plane Systolic Excursion Being Assessed by Cardiovascular Magnetic Resonance Imaging
المؤلفون المشاركون
Hoffmann, Ursula
Akin, Ibrahim
Henzler, Thomas
Papavassiliu, Theano
Kim, Seung-Hyun
Behnes, Michael
Natale, Michele
Hoffmann, Julia
Reckord, Nadine
Budjan, Johannes
Borggrefe, Martin
Bertsch, Thomas
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-01
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
This study investigates whether serum levels of galectin-3 may reflect impaired mitral annular plane systolic excursion (MAPSE) in patients undergoing cardiac magnetic resonance imaging (cMRI).
Methods.
Patients undergoing cMRI during routine clinical care were included prospectively within an all-comers design.
Blood samples for biomarker measurements were collected within 24 hours following cMRI.
Statistical analyses were performed in all patients and in three subgroups according to MAPSE (MAPSE I: ≥11 mm, MAPSE II: ≥8 mm–<11 mm, and MAPSE III: <8 mm).
Patients with right ventricular dysfunction (<50%) were excluded.
Results.
84 patients were included in the study.
Median LVEF was 59% (IQR 51–64%).
Galectin-3 correlated significantly with NT-proBNP (r=0.42, p=0.0001).
Galectin-3 increased significantly according to the different stages of impaired MAPSE (p=0.006) and was able to discriminate both patients with impaired MAPSE <11 mm (area under the curve (AUC) = 0.645, p=0.024) and <8 mm (AUC = 0.733, p=0.003).
Combining galectin-3 with NT-proBNP improved discrimination of MAPSE <8 mm (AUC 0.803, p=0.0001).
In multivariable logistic regression models galectin-3 was still associated with impaired MAPSE (MAPSE < 11 mm: odds ratio (OR) = 3.53, p=0.018; MAPSE < 8 mm: OR = 3.18, p=0.06).
Conclusions.
Galectin-3 reflects MAPSE being assessed by cardiac MRI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Seung-Hyun& Behnes, Michael& Natale, Michele& Hoffmann, Julia& Reckord, Nadine& Hoffmann, Ursula…[et al.]. 2016. Galectin-3 Reflects Mitral Annular Plane Systolic Excursion Being Assessed by Cardiovascular Magnetic Resonance Imaging. Disease Markers،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103761
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Seung-Hyun…[et al.]. Galectin-3 Reflects Mitral Annular Plane Systolic Excursion Being Assessed by Cardiovascular Magnetic Resonance Imaging. Disease Markers No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103761
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Seung-Hyun& Behnes, Michael& Natale, Michele& Hoffmann, Julia& Reckord, Nadine& Hoffmann, Ursula…[et al.]. Galectin-3 Reflects Mitral Annular Plane Systolic Excursion Being Assessed by Cardiovascular Magnetic Resonance Imaging. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103761
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103761
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر