The Relationship between Serum Endocan Levels and Depression in Alzheimer’s Disease
المؤلفون المشاركون
Kim, SoYeon
Yoon, KyungHee
Roh, Daeyoung
Kim, DoHoon
Moon, Yoo Sun
Lee, Sang Kyu
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-26
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
Growing evidence suggests that angiogenic vascular factors may be involved in the pathogenic mechanism of Alzheimer’s disease (AD), and recently endocan has been proposed as an angiogenic biomarker.
The aim of this study was to measure serum endocan levels according to the presence of depression in AD and to investigate the association among the serum endocan levels, cognitive function, and depression in these patients.
Methods.
Serum endocan levels were measured in 26 AD patients with depression, 29 AD patients without depression, and 29 healthy controls using an enzyme-linked immunosorbent assay kit.
The Mini-Mental State Examination-Korean version (MMSE-KC) and the Korean version of the Geriatric Depression Scale-Short Form (SGDS-K) were used to evaluate cognitive function and depressive symptoms, respectively.
Results.
Serum endocan levels were significantly lower in AD patients with depression than in AD patients without depression or healthy controls.
Serum endocan levels were negatively correlated with SGDS-K scores but not with MMSE-KC scores in AD patients.
Conclusions.
This study suggests that serum endocan levels might be associated with depression in AD.
Future studies are needed to investigate the pathophysiological mechanisms or the role of endocan in AD with depression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yoon, KyungHee& Kim, SoYeon& Moon, Yoo Sun& Roh, Daeyoung& Lee, Sang Kyu& Kim, DoHoon. 2016. The Relationship between Serum Endocan Levels and Depression in Alzheimer’s Disease. Disease Markers،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103785
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yoon, KyungHee…[et al.]. The Relationship between Serum Endocan Levels and Depression in Alzheimer’s Disease. Disease Markers No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103785
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yoon, KyungHee& Kim, SoYeon& Moon, Yoo Sun& Roh, Daeyoung& Lee, Sang Kyu& Kim, DoHoon. The Relationship between Serum Endocan Levels and Depression in Alzheimer’s Disease. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103785
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103785
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر