Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients
المؤلفون المشاركون
Paparoupa, Maria
Ho, Huy
Schuppert, Frank
Spineli, Loukia
Framke, Theodor
Gillissen, Adrian
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
This study evaluated the diagnostic value of D-dimer, CRP, and leucocytes count to detect an underlying pulmonary embolism (PE) in patients with pneumonia.
A predictive model of an underlying PE, based on laboratory markers and clinical symptoms, was our ultimate objective.
Overall 100 patients underwent a computed tomography angiography (CTA) of the lung: 54 with coexistence of PE and pneumonia (cases) and 46 with pneumonia without PE (controls).
Cases and controls were matched 1 : 1.
Symptoms and paraclinical findings were registered on admission.
Receiver operating characteristic (ROC) curves, search for an optimal threshold, and conditional logistic regression analysis were conducted.
D-dimer has a moderate ability to detect PE in pneumonia.
Sensitivity of D-dimer was estimated at 97.78% and specificity at 11.11%.
No optimal cut-point has acceptable diagnostic ability.
After excluding patients with sepsis, sensitivity was reduced to 96.97%, whereas specificity increased to 16.13%.
Consolidation in chest X-ray and positive D-dimer predict better an underlying PE as D-dimer itself.
Thus, discriminatory power of the prediction model (AUC of 0.740) is not much greater than D-dimer (AUC of 0.703).
No threshold that could increase the diagnostic value of D-dimer or a prediction model which is significantly better than D-dimer itself was identified.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Paparoupa, Maria& Spineli, Loukia& Framke, Theodor& Ho, Huy& Schuppert, Frank& Gillissen, Adrian. 2016. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients. Disease Markers،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103798
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Paparoupa, Maria…[et al.]. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients. Disease Markers No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103798
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Paparoupa, Maria& Spineli, Loukia& Framke, Theodor& Ho, Huy& Schuppert, Frank& Gillissen, Adrian. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103798
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103798
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر