A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions
المؤلفون المشاركون
Siadat, Amir Hossein
Jaffary, Fariba
Nilforoushzadeh, Mohammad Ali
Haftbaradaran, Elaheh
Ansari, Nazli
Kheirkhah, Abbas
المصدر
Dermatology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-11
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Cutaneous leishmaniasis is an endemic disease in Iran.
Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years.
However, the cure rate of these agents is still not favorable.
This study was carried out to compare the efficacies of intralesional glucantime with topical trichloroacetic acid 50% (TCA 50%) + glucantime and fractional carbon dioxide laser + glucantime in the treatment of cutaneous leishmaniasis.
Methods.
A total of 90 patients were randomly divided into three groups of 30 to be treated with intralesional injection of glucantime, a combination of topical TCA 50% and glucantime, or a combination of fractional laser and glucantime.
The overall clinical improvement and changes in sizes of lesions and scars were assessed and compared among three groups.
Results.
The mean duration of treatment was 6.1 ± 2.1 weeks in all patients (range: 2–12 weeks) and 6.8 ± 1.7 , 5.2 ± 1.0 , and 6.3 ± 3.0 weeks in glucantime, topical TCA plus glucantime, and fractional laser plus glucantime groups, respectively ( P = 0.011 ).
Complete improvement was observed in 10 (38.5%), 27 (90%), and 20 (87%) patients of glucantime, glucantime + TCA, and glucantime + laser groups, respectively ( P < 0.001 ).
Conclusion.
Compared to glucantime alone, the combination of intralesional glucantime and TCA 50% or fractional CO2 laser had significantly higher and faster cure rate in patients with cutaneous leishmaniasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jaffary, Fariba& Nilforoushzadeh, Mohammad Ali& Siadat, Amir Hossein& Haftbaradaran, Elaheh& Ansari, Nazli& Kheirkhah, Abbas. 2016. A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions. Dermatology Research and Practice،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1103845
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jaffary, Fariba…[et al.]. A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions. Dermatology Research and Practice No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1103845
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jaffary, Fariba& Nilforoushzadeh, Mohammad Ali& Siadat, Amir Hossein& Haftbaradaran, Elaheh& Ansari, Nazli& Kheirkhah, Abbas. A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Lesions. Dermatology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1103845
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103845
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر