Protective Effect of Mangifera indica Linn., Cocos nucifera Linn., and Averrhoa carambola Linn. Extracts against Ultraviolet B-Induced Damage in Human Keratinocytes
المؤلفون المشاركون
Tencomnao, Tewin
Pattarachotanant, Nattaporn
Ronpirin, Chalinee
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study was aimed at investigating the antioxidant activity of Mangifera indica Linn., Cocos nucifera Linn., and Averrhoa carambola Linn.
and their biological effect on human keratinocytes affected by the ultraviolet B (UVB), a major cause of cell damage and skin cancer through induction of DNA damage, production of reactive oxygen species (ROS), and apoptosis.
The richest antioxidant activity was found in ethanol fraction of M.
indica (21.32 ± 0.66 mg QE/g dry weight), while the lowest one was found in aqueous fractions of M.
indica and C.
nucifera (1.76 ± 2.10 and 1.65 ± 0.38 mg QE/g dry weight, respectively).
Ethanol and aqueous fractions of A.
carambola (250 µg/mL) significantly reduced the number of apoptotic cells.
The expression of cleaved caspase 3 in UVB-treated group was significantly greater than that in untreated group.
Both fractions of A.
carambola (50, 100, and 250 µg/mL) significantly decreased the expression of cleaved caspase 3.
Regarding the induction of DNA repair, ethanol (100 and 250 µg/mL) and aqueous (50, 100 and 250 µg/mL) fractions of A.
carambola significantly decreased the percentage of cyclobutane pyrimidine dimers (CPD).
Taken together, our results suggest that both fractions of A.
carambola may be potentially developed for dermal applications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ronpirin, Chalinee& Pattarachotanant, Nattaporn& Tencomnao, Tewin. 2016. Protective Effect of Mangifera indica Linn., Cocos nucifera Linn., and Averrhoa carambola Linn. Extracts against Ultraviolet B-Induced Damage in Human Keratinocytes. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103921
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ronpirin, Chalinee…[et al.]. Protective Effect of Mangifera indica Linn., Cocos nucifera Linn., and Averrhoa carambola Linn. Extracts against Ultraviolet B-Induced Damage in Human Keratinocytes. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103921
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ronpirin, Chalinee& Pattarachotanant, Nattaporn& Tencomnao, Tewin. Protective Effect of Mangifera indica Linn., Cocos nucifera Linn., and Averrhoa carambola Linn. Extracts against Ultraviolet B-Induced Damage in Human Keratinocytes. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103921
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103921
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر