GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia
المؤلفون المشاركون
Mothana, R. A. A.
Al-Sohaibani, Mohammed
Khaled, Jamal M.
Alatar, Abdulrahman
Kurkcuoglu, Mine
Baser, Husnu C.
al-Said, Mansour
al-Harbi, Naif O.
al-Yahya, Mohammed
Rafatullah, Syed
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-12
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Liver disease is a worldwide problem.
It represents one of the main causes of morbidity and mortality in humans.
Achillea biebersteinii is used as herbal remedy for various ailments including liver diseases.
But the scientific basis for its medicinal use remains unknown.
Thus, this research was undertaken to evaluate the efficiency of A.
biebersteinii essential oil (ABEO) (0.2 mL/kg) in the amelioration of CCl4-induced hepatotoxicity in rodent model.
Moreover, the chemical content of the oil was investigated using GC and GC-MS.
The following biochemical parameters were evaluated: serum glutamic oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), gamma-glutamyl-transpeptidase (γ-GGT), alkaline phosphatase (ALP), and total bilirubin.
Furthermore, lipid profile, malondialdehyde (MDA), nonprotein sulfhydryl (NP-SH), and total protein (TP) contents in liver tissue were estimated.
44 components (92.0%) of the total oil have been identified by GC-MS analysis where α-terpinene and p -cymene were the most abundant.
The high serum enzymatic (GOT, GPT, GGT, and ALP) and bilirubin concentrations as well as the level of MDA, NP-SH, and TP contents in liver tissues were significantly reinstated towards normalization by the ABEO.
Histopathological study further confirmed these findings.
In addition, ABEO showed mild antioxidant activity in 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and β-carotene-linoleic acid assays.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Said, Mansour& Mothana, R. A. A.& al-Yahya, Mohammed& Rafatullah, Syed& Al-Sohaibani, Mohammed& Khaled, Jamal M.…[et al.]. 2016. GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103934
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Said, Mansour…[et al.]. GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103934
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Said, Mansour& Mothana, R. A. A.& al-Yahya, Mohammed& Rafatullah, Syed& Al-Sohaibani, Mohammed& Khaled, Jamal M.…[et al.]. GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103934
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103934
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر