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Comparison of the Effect of Velvet Antler from Different Sections on Longitudinal Bone Growth of Adolescent Rats
المؤلفون المشاركون
Kim, Hye Kyung
Kim, Myung-Gyou
Leem, Kang-Hyun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The aim of this study was to compare the effectiveness of velvet antler (VA) from different sections for promoting longitudinal bone growth in growing rats.
VA was divided into upper (VAU), middle (VAM), and basal sections (VAB).
An in vivo study was performed to examine the effect on longitudinal bone growth in adolescent rats.
In addition, in vitro osteogenic activities were examined using osteoblastic MG-63 cells.
VA promoted longitudinal bone growth and height of the growth plate in adolescent rats.
Bone morphogenetic protein-2 (BMP-2) in growth plate of VA group was highly expressed compared with control.
The anabolic effect of VA on bone was further supported by in vitro study.
VA enhanced the proliferation, differentiation, and mineralization of MG-63 cells.
The mRNA expressions of osteogenic genes such as collagen, alkaline phosphatase, and osteocalcin were increased by VA treatment.
These effects of in vivo and in vitro study were decreased from upper to basal sections of VA.
In conclusion, VA treatment promotes longitudinal bone growth in growing rats through enhanced BMP-2 expression, osteogenic activities, and bone matrix gene expressions.
In addition, present study provides evidence for the regional differences in the effectiveness of velvet antler for longitudinal bone growth.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Hye Kyung& Kim, Myung-Gyou& Leem, Kang-Hyun. 2016. Comparison of the Effect of Velvet Antler from Different Sections on Longitudinal Bone Growth of Adolescent Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103940
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Hye Kyung…[et al.]. Comparison of the Effect of Velvet Antler from Different Sections on Longitudinal Bone Growth of Adolescent Rats. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103940
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Hye Kyung& Kim, Myung-Gyou& Leem, Kang-Hyun. Comparison of the Effect of Velvet Antler from Different Sections on Longitudinal Bone Growth of Adolescent Rats. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103940
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103940
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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