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Acupuncture Induces the Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Traumatic Brain Injury
المؤلفون المشاركون
Jiang, Shuting
Chen, Weihao
Zhang, Yimin
Zhang, Yujuan
Chen, Ailian
Dai, Qiufu
Lin, Shujun
Lin, Hanyu
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To investigate whether acupuncture induced the proliferation and differentiation of endogenous neural stem cells (NSCs) in a rat model of traumatic brain injury (TBI).
Methods.
104 Sprague-Dawley rats were randomly divided into normal, model, and acupuncture groups.
Each group was subdivided into three-day (3 d), seven-day (7 d), and fourteen-day (14 d) groups.
The rat TBI model was established using Feeney’s freefall epidural impact method.
The rats in the acupuncture group were treated at acupoints (Baihui, Shuigou, Fengfu, Yamen, and bilateral Hegu).
The normal and model groups did not receive acupuncture.
The establishment of the rat TBI model and the therapeutic effect of acupuncture were assessed using neurobehavioral scoring and hematoxylin-eosin staining.
The proliferation and differentiation of NSCs in TBI rats were analyzed using immunofluorescence microscopy.
Results.
The levels of nestin-expressing cells and bromodeoxyuridine/glial fibrillary acidic protein- (BrdU/GFAP-) and BrdU/S100 calcium-binding protein B-positive and BrdU/microtubule-associated protein 2- and BrdU/galactocerebrosidase-positive cells were more significantly increased at various time points in the acupuncture group than in the model group (P<0.01), except for a decreased level of BrdU/GFAP-positive cells at 7 d and 14 d.
Conclusion.
Acupuncture induced the proliferation and differentiation of NSCs, thereby promoting neural repair in the TBI rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jiang, Shuting& Chen, Weihao& Zhang, Yimin& Zhang, Yujuan& Chen, Ailian& Dai, Qiufu…[et al.]. 2016. Acupuncture Induces the Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Traumatic Brain Injury. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103959
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jiang, Shuting…[et al.]. Acupuncture Induces the Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Traumatic Brain Injury. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103959
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jiang, Shuting& Chen, Weihao& Zhang, Yimin& Zhang, Yujuan& Chen, Ailian& Dai, Qiufu…[et al.]. Acupuncture Induces the Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Traumatic Brain Injury. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103959
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103959
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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