Attenuation of Oxidative Stress of Erythrocytes by Plant-Derived Flavonoids, Orientin and Luteolin
المؤلفون المشاركون
Gong, Yuewen
An, Fang
Wang, Shulin
Yuan, Danhua
Wang, Shuhua
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Erythrocytes are easy to be injured by oxidative stress in their lifespan.
Although there are several chemicals such as vitamin C (VC) that would be able to reduce oxidative stress, natural herbal products still remain an interesting research area.
The current study investigated the effects of two plant-derived flavonoids, orientin and luteolin, on erythrocytes and their possible mechanisms.
This experiment was divided into nine groups, which were normal group, model group, VC control group, and treated groups with different doses of orientin and luteolin (10, 20, and 40 μg/mL), respectively.
Hemolysis rate was determined by spectrophotometry.
Antioxidative enzyme and products were evaluated by different methods.
Erythrocyte cell surface and cellular structure were observed with scanning or transmission electron microscope, respectively.
Oxidative stress induced significant increase in hemolysis rate of erythrocytes.
Orientin or luteolin ameliorated hemolysis of erythrocytes in oxidative stress in a dose-dependent manner.
Both orientin and luteolin reduced oxidative products and increased antioxidative enzyme activities.
Moreover, orientin and luteolin attenuated oxidative stress induced damage of erythrocyte cell surface morphology and cellular structure.
In conclusion, orientin and luteolin could protect human erythrocytes from oxidative damage by attenuating oxidative stress, protecting antioxidative enzyme activities, and preserving integrity of erythrocyte structure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
An, Fang& Wang, Shulin& Yuan, Danhua& Gong, Yuewen& Wang, Shuhua. 2016. Attenuation of Oxidative Stress of Erythrocytes by Plant-Derived Flavonoids, Orientin and Luteolin. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104066
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
An, Fang…[et al.]. Attenuation of Oxidative Stress of Erythrocytes by Plant-Derived Flavonoids, Orientin and Luteolin. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104066
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
An, Fang& Wang, Shulin& Yuan, Danhua& Gong, Yuewen& Wang, Shuhua. Attenuation of Oxidative Stress of Erythrocytes by Plant-Derived Flavonoids, Orientin and Luteolin. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104066
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104066
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر