Identification of Plants That Inhibit Lipid Droplet Formation in Liver Cells: Rubus suavissimus Leaf Extract Protects Mice from High-Fat Diet-Induced Fatty Liver by Directly Affecting Liver Cells
المؤلفون المشاركون
Takahashi, Tomohiro
Sugawara, Wataru
Takiguchi, Yuya
Takizawa, Kento
Nakabayashi, Ami
Nakamura, Mitsuo
Nagano-Ito, Michiyo
Ichikawa, Shinichi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Fatty liver disease is a condition in which abnormally large numbers of lipid droplets accumulate in liver cells.
Fatty liver disease induces inflammation under conditions of oxidative stress and may result in cancer.
To identify plants that protect against fatty liver disease, we examined the inhibitory effects of plant extracts on lipid droplet formation in mouse hepatoma cells.
A screen of 98 water extracts of plants revealed 4 extracts with inhibitory effects.
One of these extracts, Rubus suavissimus S.
Lee (Tien-cha or Chinese sweet tea) leaf extract, which showed strong inhibitory effects, was tested in a mouse fatty liver model.
In these mouse experiments, intake of the plant extract significantly protected mice against fatty liver disease without affecting body weight gain.
Our results suggest that RSE directly affects liver cells and protects them from fatty liver disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takahashi, Tomohiro& Sugawara, Wataru& Takiguchi, Yuya& Takizawa, Kento& Nakabayashi, Ami& Nakamura, Mitsuo…[et al.]. 2016. Identification of Plants That Inhibit Lipid Droplet Formation in Liver Cells: Rubus suavissimus Leaf Extract Protects Mice from High-Fat Diet-Induced Fatty Liver by Directly Affecting Liver Cells. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104136
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takahashi, Tomohiro…[et al.]. Identification of Plants That Inhibit Lipid Droplet Formation in Liver Cells: Rubus suavissimus Leaf Extract Protects Mice from High-Fat Diet-Induced Fatty Liver by Directly Affecting Liver Cells. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104136
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takahashi, Tomohiro& Sugawara, Wataru& Takiguchi, Yuya& Takizawa, Kento& Nakabayashi, Ami& Nakamura, Mitsuo…[et al.]. Identification of Plants That Inhibit Lipid Droplet Formation in Liver Cells: Rubus suavissimus Leaf Extract Protects Mice from High-Fat Diet-Induced Fatty Liver by Directly Affecting Liver Cells. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104136
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104136
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر