Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites
المؤلفون المشاركون
Chen, Xiaojia
Wan, Jian-Bo
Zhang, Xiao-Jing
Shui, Yan-Mei
Gao, Jian-Li
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-19، 19ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-30
دولة النشر
مصر
عدد الصفحات
19
التخصصات الرئيسية
الملخص EN
Recently, most anticancer drugs are derived from natural resources such as marine, microbial, and botanical sources, but the low success rates of chemotherapies and the development of multidrug resistance emphasize the importance of discovering new compounds that are both safe and effective against cancer.
Ginseng types, including Asian ginseng, American ginseng, and notoginseng, have been used traditionally to treat various diseases, due to their immunomodulatory, neuroprotective, antioxidative, and antitumor activities.
Accumulating reports have shown that ginsenosides, the major active component of ginseng, were helpful for tumor treatment.
20(S)-Protopanaxadiol (PDS) and 20(S)-protopanaxatriol saponins (PTS) are two characteristic types of triterpenoid saponins in ginsenosides.
PTS holds capacity to interfere with crucial metabolism, while PDS could affect cell cycle distribution and prodeath signaling.
This review aims at providing an overview of PTS and PDS, as well as their metabolites, regarding their different anticancer effects with the proposal that these compounds might be potent additions to the current chemotherapeutic strategy against cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Xiaojia& Zhang, Xiao-Jing& Shui, Yan-Mei& Wan, Jian-Bo& Gao, Jian-Li. 2016. Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1104225
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Xiaojia…[et al.]. Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-19.
https://search.emarefa.net/detail/BIM-1104225
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Xiaojia& Zhang, Xiao-Jing& Shui, Yan-Mei& Wan, Jian-Bo& Gao, Jian-Li. Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1104225
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104225
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر