Inhibition of Asthma in OVA Sensitized Mice Model by a Traditional Uygur Herb Nepeta bracteata Benth.
المؤلفون المشاركون
Ding, Jianbing
Pang, Nannan
Wang, Jing
Li, Feng-sen
Tian, Ge
Jiang, Min
Zhang, Hong-ping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-17
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Asthma is a chronic lung inflammation which affects many people.
As current therapies for asthma mainly rely on administration of glucocorticoids and have many side effects, new therapy is needed.
In this study, we investigated Nepeta bracteata Benth., a traditional Uygur Herb, for its therapeutics effect in OVA induced asthmatic mice model.
Treatment of OVA sensitized asthma mice with extract from Nepeta bracteata Benth.
demonstrated improved lung pathology, as well as reduced infiltration of eosinophil and neutrophil.
Nepeta bracteata Benth.
extract also contributed to the rebalance of Th17/Treg cell via decreasing the Th17 cell and increasing the Treg, which was corresponding with the inhibited Th17 cytokine response and increased IL-10 level.
Moreover, the reduced TGF-β level and Smad2/3 protein level also suggested that Nepeta bracteata Benth.
extract could inhibit TGF-β mediated airway remodelling as well.
Taken together, these data suggested that Nepeta bracteata Benth.
may be a novel candidate for future antiasthma drug development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Jing& Li, Feng-sen& Pang, Nannan& Tian, Ge& Jiang, Min& Zhang, Hong-ping…[et al.]. 2016. Inhibition of Asthma in OVA Sensitized Mice Model by a Traditional Uygur Herb Nepeta bracteata Benth.. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104228
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Jing…[et al.]. Inhibition of Asthma in OVA Sensitized Mice Model by a Traditional Uygur Herb Nepeta bracteata Benth.. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104228
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Jing& Li, Feng-sen& Pang, Nannan& Tian, Ge& Jiang, Min& Zhang, Hong-ping…[et al.]. Inhibition of Asthma in OVA Sensitized Mice Model by a Traditional Uygur Herb Nepeta bracteata Benth.. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104228
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104228
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر