Exploratory, Phase II Controlled Trial of Shiunko Ointment Local Application Twice a Day for 4 Weeks in Ethiopian Patients with Localized Cutaneous Leishmaniasis
المؤلفون المشاركون
Na-Bangchang, Kesara
Ahmed, Oumer
Hussein, Jemal
Hirayama, Kenji
Kongjam, Panida
Karbwang, Juntra
Aseffa, Abraham
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The clinical efficacy and safety of Shiunko ointment (phase II clinical trial) was investigated in 40 Ethiopian patients with cutaneous leishmaniasis.
Patients were randomized to receive treatment with Shiunko ointment or placebo ( n = 20 , each), applied on the lesion twice a day for 4 weeks.
Clinicoparasitological assessments were performed before treatment, weekly for 4 weeks, and then 4, 8, and 12 weeks after the end of treatment.
A marked reduction in lesion size was observed on week 16 of treatment in the Shiunko compared with placebo group (69% and 22% reduction, resp.).
The overall rate of lesion reduction during the four weeks of treatment was significantly faster in the Shiunko group.
Shiunko provided significant effect on wound closure in patients with ulcerated lesion.
The clinical efficacy and tolerability of Shiunko were comparable to placebo with regard to its clinicoparasitological response (cure rate and parasitological clearance).
Results of this preliminary study may suggest that Shiunko could be useful as adjuvant or as complementary treatment, not as alternatives to current treatment.
Its attractive action includes fast lesion healing with a significantly smaller lesion at week 16 of treatment compared with placebo.
In addition, its action was promoted in ulcerative lesions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Na-Bangchang, Kesara& Ahmed, Oumer& Hussein, Jemal& Hirayama, Kenji& Kongjam, Panida& Aseffa, Abraham…[et al.]. 2016. Exploratory, Phase II Controlled Trial of Shiunko Ointment Local Application Twice a Day for 4 Weeks in Ethiopian Patients with Localized Cutaneous Leishmaniasis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104251
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Na-Bangchang, Kesara…[et al.]. Exploratory, Phase II Controlled Trial of Shiunko Ointment Local Application Twice a Day for 4 Weeks in Ethiopian Patients with Localized Cutaneous Leishmaniasis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104251
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Na-Bangchang, Kesara& Ahmed, Oumer& Hussein, Jemal& Hirayama, Kenji& Kongjam, Panida& Aseffa, Abraham…[et al.]. Exploratory, Phase II Controlled Trial of Shiunko Ointment Local Application Twice a Day for 4 Weeks in Ethiopian Patients with Localized Cutaneous Leishmaniasis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104251
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104251
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر