Dendrobium officinale Prevents Early Complications in Streptozotocin-Induced Diabetic Rats
المؤلفون المشاركون
Hou, Shao-Zhen
Liang, Chu-yan
Liu, Hua-zhen
Zhu, Dong-mei
Wu, Ya-yun
Liang, Jian
Zhao, Ya
Guo, Jian-ru
Huang, Song
Lai, Xiao-Ping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Dendrobium officinale (DO) Kimura et Migo is a precious Chinese herb that is considered beneficial for health due to its antioxidant and antidiabetes properties, and so on.
In this research, we try to determine the preventive effect of DO on the early complications of STZ-induced diabetic rats.
Methods.
Type 1 diabetic rats were produced with a single intraperitoneal injection of STZ (50 mg/kg).
DO (1 g/kg/day) was then orally administered for 5 weeks.
Blood glucose, TC, TG, BUN, CREA, and GSH-PX levels were determined, and electroretinographic activity and hypoalgesia were investigated.
Pathological sections of the eyes, hearts, aortas, kidneys, and livers were analyzed.
Results.
Treatment with DO significantly attenuated the serum levels of TC, TG, BUN, and CREA, markedly increased the amplitudes of ERG a- and b-waves and Ops, and reduced the hypoalgesia and histopathological changes of vital organs induced by hyperglycemia.
The protective effect of DO in diabetic rats may be associated with its antioxidant activity, as evidenced by the marked increase in the serum level of glutathione peroxidase.
However, DO had no significant effect on blood glucose levels and bodyweight of diabetic rats.
Conclusions.
DO supplementation is an effective treatment to prevent STZ-induced diabetic complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hou, Shao-Zhen& Liang, Chu-yan& Liu, Hua-zhen& Zhu, Dong-mei& Wu, Ya-yun& Liang, Jian…[et al.]. 2016. Dendrobium officinale Prevents Early Complications in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104282
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hou, Shao-Zhen…[et al.]. Dendrobium officinale Prevents Early Complications in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1104282
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hou, Shao-Zhen& Liang, Chu-yan& Liu, Hua-zhen& Zhu, Dong-mei& Wu, Ya-yun& Liang, Jian…[et al.]. Dendrobium officinale Prevents Early Complications in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104282
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104282
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر