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Antibacterial Activity of Salvadora persica L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates
المؤلفون المشاركون
Al-Ayed, Mohamed Saeed Zayed
Asaad, Ahmed Morad
Qureshi, Mohamed Ansar
Attia, Hany Goda
AlMarrani, Abduljabbar Hadi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-19
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Much effort has focused on examining the inhibitory effect of Salvadora persica (miswak) on oral microorganisms, but information concerning its antibacterial activity against other human pathogens, particularly multidrug resistant (MDR) isolates, is scarce.
Therefore, this study aimed to assess the in vitro antibacterial activities of Salvadora persica L.
extracts against 10 MDR bacterial clinical isolates other than oral pathogens.
The antibacterial activity of aqueous and methanol miswak extracts was assessed using the agar dilution and minimum inhibitory concentration (MIC) methods.
Overall, the 400 mg/mL of miswak extract was the most effective on all strains.
The methanol extract exhibited a stronger antibacterial activity against Gram-negative (3.3–13.6 mm) than Gram-positive (1.8–8.3 mm) bacteria.
The lowest MIC value was seen for E.
coli (0.39, 1.56 µg/mL), followed by Streptococcus pyogenes (1.56 µg/mL).
The highest MIC value (6.25, 12.5 µg/mL) was recorded for methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, and Stenotrophomonas maltophilia.
This study demonstrates, for the first time, the moderate to strong antibacterial activity of miswak extracts against all tested MDR-pathogens.
Methanol extract appears to be a potent antimicrobial agent that could be considered as complementary and alternative medicine against resistant pathogens.
Further studies on a large number of MDR organisms are necessary to investigate and standardize the inhibitory effect of miswak extracts against these emerging pathogens.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Al-Ayed, Mohamed Saeed Zayed& Asaad, Ahmed Morad& Qureshi, Mohamed Ansar& Attia, Hany Goda& AlMarrani, Abduljabbar Hadi. 2016. Antibacterial Activity of Salvadora persica L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104320
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Al-Ayed, Mohamed Saeed Zayed…[et al.]. Antibacterial Activity of Salvadora persica L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1104320
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Al-Ayed, Mohamed Saeed Zayed& Asaad, Ahmed Morad& Qureshi, Mohamed Ansar& Attia, Hany Goda& AlMarrani, Abduljabbar Hadi. Antibacterial Activity of Salvadora persica L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104320
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104320
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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