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Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience
المؤلفون المشاركون
Kuriry, H.
Aljumah, Abdulrahman A.
AlZunaitan, Mohammed
Al Ghobain, Mohammed
Al Muaikeel, Mohamed
Al Olayan, Ashwaq
Azzumeea, Fahad
AlAlwan, Abduljaleel
AlGhamdi, Hamdan
Almutairi, Bader
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-25
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the risk factors, clinical characteristics, treatment modalities, and outcomes in Saudi patients with HCC and propose points for early detection of the disease.
Methods.
Patients were stratified according to underlying risk factors for the development of HCC.
Barcelona Clinic Liver Cancer (BCLC) was used for cancer staging.
Treatment was classified into surgical resection/liver transplantation; locoregional ablation therapy; transarterial embolization; systemic chemotherapy; and best supportive care.
Results.
A total of 235 patients were included.
Males had higher tumor size and incidence of portal vein thrombosis.
Viral hepatitis was a risk factor in 75.7%.
The most common BCLC stages were B (34.5%) and A (33.6%), and the most common radiological presentation was a single nodule of less than 5 cm.
Metastases were present in 13.2%.
Overall, 77 patients (32.8%) underwent a potentially curative treatment as the initial therapy.
The most commonly utilized treatment modality was chemoembolization with 113 sessions in 71 patients.
The overall median survival was 15.97 ± 27.18 months.
Conclusion.
HCC in Saudi Arabia is associated with high prevalence of HCV.
Potentially curative therapies were underutilized in our patients.
Cancer stage BCLC-B was the most frequent (34.5%) followed by BCLC-A (33.6%).
The overall median survival was shorter than other studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aljumah, Abdulrahman A.& Kuriry, H.& AlZunaitan, Mohammed& Al Ghobain, Mohammed& Al Muaikeel, Mohamed& Al Olayan, Ashwaq…[et al.]. 2016. Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104605
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aljumah, Abdulrahman A.…[et al.]. Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1104605
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aljumah, Abdulrahman A.& Kuriry, H.& AlZunaitan, Mohammed& Al Ghobain, Mohammed& Al Muaikeel, Mohamed& Al Olayan, Ashwaq…[et al.]. Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104605
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104605
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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