Do NSAIDs and ASA Cause More Upper Gastrointestinal Bleeding in Elderly than Adults?
المؤلفون المشاركون
Okuturlar, Yıldız
Harmankaya, Özlem
Kocoglu, Hakan
Oguz, Basak
Dogan, Hakan
Hursitoglu, Mehmet
Altuntas, Yuksel
Kumbasar, Abdulbaki
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
NSAIDs and ASA may cause upper gastrointestinal bleeding (UGIB) both in adults and in elderly.
There is no study that compares this increased bleeding risk between adult and elderly subjects.
Methods.
A total of 524 patients with UGIB were included in this study.
The data of patients were, respectively, analyzed.
Results.
NSAIDs and ASA-associated UGIB rates were similar between <65 years (345 patients) (group 1) and ≥65 years (179 patients) (group 2) (28.4% versus 23.5%, p=0.225 and 13% versus 19%, p=0.071, resp.).
Warfarin-associated UGIB was found significantly higher in group 2 than group 1.
Elderly patients with NSAID-associated UGIB had significantly higher length of stay (LoS) and CoH than adult patients with NSAID-associated UGIB (p=0.002 and 0.001, resp.).
Elderly patients with ASA-associated UGIB had significantly higher CoH than adult patients with NSAID-associated UGIB.
Conclusions.
Using NSAIDs without gastroprotective drugs or using ASA with gastroprotective drugs in elderly patients is as safe as in adult patients.
Not only should adding gastroprotective drugs to ASA or NSAID be based on their risk of UGIB, but the cost of hospitalization of ASA or NSAID-associated UGIB should be considered.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kocoglu, Hakan& Oguz, Basak& Dogan, Hakan& Okuturlar, Yıldız& Hursitoglu, Mehmet& Harmankaya, Özlem…[et al.]. 2016. Do NSAIDs and ASA Cause More Upper Gastrointestinal Bleeding in Elderly than Adults?. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104808
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kocoglu, Hakan…[et al.]. Do NSAIDs and ASA Cause More Upper Gastrointestinal Bleeding in Elderly than Adults?. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1104808
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kocoglu, Hakan& Oguz, Basak& Dogan, Hakan& Okuturlar, Yıldız& Hursitoglu, Mehmet& Harmankaya, Özlem…[et al.]. Do NSAIDs and ASA Cause More Upper Gastrointestinal Bleeding in Elderly than Adults?. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104808
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104808
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر