Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China
المؤلفون المشاركون
Lan, Chun-Hui
Han, Ran
Hu, Jiali
Lu, Hong
Jiang, Ming-Wan
Tan, Ke-Wen
Peng, Zhong
Fang, Dian-Chun
Wu, Xiao-Ling
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This study was to investigate the antibiotic resistance profile of H.
pylori and the distribution of CYP2C19 gene polymorphism in rural population of Chongqing, China.
214 and 111 strains of H.
pylori were isolated from rural and urban patients, respectively.
99.53%, 20.09%, and 23.36% of the isolates in rural patients were found to be resistant to metronidazole, clarithromycin, and levofloxacin, while the resistant rate in urban patients was 82.88%, 19.82%, and 24.32%.
The multiple antibiotic resistance percentage significantly increased from 28.26% (below 45 years) to 41.80% (above 45 years) in rural patients.
Up to 44.39%, 45.79%, and 9.81% of rural patients from whom H.
pylori was isolated were found to be extensive metabolizers, intermediate metabolizers, and poor metabolizers.
No correlation was observed between antibiotic resistance profile of H.
pylori and genetic polymorphism of CYP2C19 among rural population.
There was a high prevalence of H.
pylori strains resistant to metronidazole, clarithromycin, and levofloxacin in rural patients in Chongqing, China.
The choice of therapy in this area should be based on local susceptibility patterns.
Amoxicillin, gentamicin, and furazolidone are recommended as the first-line empiric regimen.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Han, Ran& Lu, Hong& Jiang, Ming-Wan& Tan, Ke-Wen& Peng, Zhong& Hu, Jiali…[et al.]. 2016. Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104815
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Han, Ran…[et al.]. Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1104815
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Han, Ran& Lu, Hong& Jiang, Ming-Wan& Tan, Ke-Wen& Peng, Zhong& Hu, Jiali…[et al.]. Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104815
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104815
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر