Evaluation of Subclinical Hypothyroidism in Children and Adolescents: A Single-Center Study
المؤلفون المشاركون
Malecka-Tendera, Ewa
Gawlik, Aneta
Such, Kamila
Dejner, Aleksandra
Zachurzok, Agnieszka
Antosz, Aleksandra
Gawlik, Tomasz
Wasniewska, Malgorzata
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The main purpose of our retrospective study was to evaluate the medical care of the patients with subclinical hypothyroidism (sHT) and to investigate the rationale for administering L-thyroxine (LT-4) to young sHT patients.
Patients and Methods.
Based on a retrospective review of the charts of 261 patients referred to the Endocrinology Outpatient Clinic between 2009 and 2014 with suspicion of sHT, 55 patients were enrolled for further analysis.
Data collected was baseline age, anthropometric measurements, serum TSH, fT4, fT3, anti-thyroid autoantibodies, positive family history, absence/presence of clinical symptoms, length of follow-up, and data concerning LT-4 therapy (therapy: T1; no therapy: T0).
Results.
T1 encompassed 33 (60.0%) patients.
There were no differences between T1 and T0 ( p > 0.05 ) with regard to age, TSH concentrations, BMI Z -score, and hSDS values, though follow-up was longer in T1 ( p < 0.01 ).
Four (11.8%) children in T1 and none in T0 had a positive family history of thyroid disorders.
Fifteen (68.2%) patients in group T0 became euthyroid.
One (1.8%) girl (T1) developed overt hypothyroidism.
Conclusions.
A small percentage of patients can proceed to overt hypothyroidism.
Only positive family history seemed to influence the decision to initiate LT-4 therapy.
Further prospective studies are warranted in order to establish treatment indications, if any, and the mean recommended dosage of LT-4.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Such, Kamila& Gawlik, Aneta& Dejner, Aleksandra& Wasniewska, Malgorzata& Zachurzok, Agnieszka& Antosz, Aleksandra…[et al.]. 2016. Evaluation of Subclinical Hypothyroidism in Children and Adolescents: A Single-Center Study. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1105765
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Such, Kamila…[et al.]. Evaluation of Subclinical Hypothyroidism in Children and Adolescents: A Single-Center Study. International Journal of Endocrinology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1105765
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Such, Kamila& Gawlik, Aneta& Dejner, Aleksandra& Wasniewska, Malgorzata& Zachurzok, Agnieszka& Antosz, Aleksandra…[et al.]. Evaluation of Subclinical Hypothyroidism in Children and Adolescents: A Single-Center Study. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1105765
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105765
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر