Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature
المؤلفون المشاركون
Vera, J.
Venegas, C.
Lagunas, C.
Muñoz, S.
Oyarce, S.
Muñoz, K.
Valenzuela, Francisco J.
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-22
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The circadian system is a supraphysiological system that modulates different biological functions such as metabolism, sleep-wake, cellular proliferation, and body temperature.
Different chronodisruptors have been identified, such as shift work, feeding time, long days, and stress.
The environmental changes and our modern lifestyle can alter the circadian system and increase the risk of developing pathologies such as cancer, preeclampsia, diabetes, and mood disorder.
This system is organized by transcriptional/tranductional feedback loops of clock genes Clock, Bmal1, Per1–3, and Cry1-2.
How molecular components of the clock are able to influence the development of diseases and their risk relation with genetic components of polymorphism of clock genes is unknown.
This research describes different genetic variations in the population and how these are associated with risk of cancer, metabolic diseases such as diabetes, obesity, and dyslipidemias, and also mood disorders such as depression, bipolar disease, excessive alcohol intake, and infertility.
Finally, these findings will need to be implemented and evaluated at the level of genetic interaction and how the environment factors trigger the expression of these pathologies will be examined.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valenzuela, Francisco J.& Vera, J.& Venegas, C.& Muñoz, S.& Oyarce, S.& Muñoz, K.…[et al.]. 2016. Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1105830
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valenzuela, Francisco J.…[et al.]. Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature. International Journal of Endocrinology No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1105830
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valenzuela, Francisco J.& Vera, J.& Venegas, C.& Muñoz, S.& Oyarce, S.& Muñoz, K.…[et al.]. Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1105830
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105830
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر